FBXO44 Antibody

Code CSB-PA008509GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
FBXO44
Alternative Names
5730411K09 antibody; AV001623 antibody; DKFZp781J0852 antibody; F box gene 3 antibody; F box only protein 44 antibody; F box only protein 6a antibody; F box protein 44 antibody; F box protein FBX30 antibody; F box/G domain protein 3 antibody; F-box only protein 44 antibody; F-box protein FBX30 antibody; F-box/G-domain protein 3 antibody; FBG3 antibody; FBX30 antibody; FBX44 antibody; FBX44_HUMAN antibody; FBX6A antibody; Fbxo44 antibody; Fbxo6a antibody; MGC14140 antibody; RGD1562463 antibody
Species Reactivity
Human,Mouse,Rat
Immunogen
Human FBXO44
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Gene References into Functions
  1. Although the overall structure of FBG3 is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3. PMID: 26460611
  2. FBXO44-mediated degradation of RGS2 protein uniquely depends on a Cul4B/DDB1 complex. PMID: 25970626
  3. FBXO44 mediates BRCA1 ubiquitination and degradation PMID: 23086937
  4. Skp1 and Fbg3 were co-expressed in E. coli. The plate-shaped crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 34.1, b = 76.6, c = 193.9 A and one molecule per asymmetric unit. PMID: 20057081
Tissue Specificity
Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver.
Database Links

HGNC: 24847

OMIM: 609111

KEGG: hsa:93611

STRING: 9606.ENSP00000251547

UniGene: Hs.556006

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