FBXO44 Antibody, FITC conjugated

Datasheet

Code	CSB-PA872497LC01HU
Size	US$166
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) FBXO44 Polyclonal antibody

Uniprot No.

Q9H4M3

Target Names

FBXO44

Alternative Names

5730411K09 antibody; AV001623 antibody; DKFZp781J0852 antibody; F box gene 3 antibody; F box only protein 44 antibody; F box only protein 6a antibody; F box protein 44 antibody; F box protein FBX30 antibody; F box/G domain protein 3 antibody; F-box only protein 44 antibody; F-box protein FBX30 antibody; F-box/G-domain protein 3 antibody; FBG3 antibody; FBX30 antibody; FBX44 antibody; FBX44_HUMAN antibody; FBX6A antibody; Fbxo44 antibody; Fbxo6a antibody; MGC14140 antibody; RGD1562463 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human F-box only protein 44 protein (1-224AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.

Gene References into Functions

Although the overall structure of FBG3 is similar to that of Fbs1, the residues that form the Fbs1 carbohydrate-binding pocket failed to be superposed with the corresponding residues of FBG3. PMID: 26460611
FBXO44-mediated degradation of RGS2 protein uniquely depends on a Cul4B/DDB1 complex. PMID: 25970626
FBXO44 mediates BRCA1 ubiquitination and degradation PMID: 23086937
Skp1 and Fbg3 were co-expressed in E. coli. The plate-shaped crystals belonged to space group P2(1)2(1)2(1), with unit-cell parameters a = 34.1, b = 76.6, c = 193.9 A and one molecule per asymmetric unit. PMID: 20057081

Tissue Specificity

Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver.

Database Links

HGNC: 24847

OMIM: 609111

KEGG: hsa:93611

STRING: 9606.ENSP00000251547

UniGene: Hs.556006

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Service

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Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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