Code | CSB-PA004640 |
Size | US$167 |
Image |
Uniprot No. | Q9C0B1 | ||||||
Target Names | FTO | ||||||
Alternative Names | FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein | ||||||
Raised in | Rabbit | ||||||
Species Reactivity | Human,Mouse,Rat | ||||||
Immunogen | Synthesized peptide derived from the N-terminal region of Human FTO. | ||||||
Immunogen Species | Homo sapiens (Human) | ||||||
Conjugate | Non-conjugated | ||||||
Isotype | IgG | ||||||
Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||||||
Form | Liquid | ||||||
Tested Applications | WB, ELISA | ||||||
Recommended Dilution |
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Protocols | Western Blotting(WB) Protocol ELISA Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine |
Involvement in disease | Growth retardation, developmental delay, and facial dysmorphism (GDFD); Obesity (OBESITY) |
Subcellular Location | Nucleus, Nucleus speckle |
Protein Families | Fto family |
Tissue Specificity | Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary. |
Database Links |
HGNC: 24678 OMIM: 601665 KEGG: hsa:79068 STRING: 9606.ENSP00000418823 UniGene: Hs.528833 |
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Email: support@cusabio.com
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