Product Details

Uniprot No.

Q9C0B1

Target Names

FTO

Alternative Names

FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from the N-terminal region of Human FTO.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
ELISA	1:20000

Protocols

Western Blotting(WB) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Still Have Questions?

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Target Data

Function	Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine
Involvement in disease	Growth retardation, developmental delay, and facial dysmorphism (GDFD); Obesity (OBESITY)
Subcellular Location	Nucleus, Nucleus speckle
Protein Families	Fto family
Tissue Specificity	Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary.
Database Links	HGNC: 24678 OMIM: 601665 KEGG: hsa:79068 STRING: 9606.ENSP00000418823 UniGene: Hs.528833

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Check Code：

Code	CSB-PA004640
Size	US$167
Image	Western Blot analysis of K562 cells using FTO Polyclonal Antibody

FTO Antibody

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