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| Code | CSB-PA004640 |
| Size | US$167 |
| Uniprot No. | Q9C0B1 |
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| Protocols | Western Blotting(WB) Protocol ELISA Protocol |
| Immunogen | Synthesized peptide derived from the N-terminal region of Human FTO. |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Tested Applications | WB,ELISA;WB:1/500-1/2000.ELISA:1/20000 |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Alias | FTO; KIAA1752; Alpha-ketoglutarate-dependent dioxygenase FTO; Fat mass and obesity-associated protein |
| Immunogen Species | Homo sapiens (Human) |
| Target Names | FTO |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| References |
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| Function | Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine |
| Involvement in disease | Growth retardation, developmental delay, and facial dysmorphism (GDFD); Obesity (OBESITY) |
| Subcellular Location | Nucleus, Nucleus speckle |
| Protein Families | Fto family |
| Tissue Specificity | Ubiquitously expressed, with relatively high expression in adrenal glands and brain; especially in hypothalamus and pituitary. |
| Database Links |
HGNC: 24678 OMIM: 601665 KEGG: hsa:79068 STRING: 9606.ENSP00000418823 UniGene: Hs.528833 |
FTO Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-RA880154A0HU | FTO Antibody | Human | ELISA, WB, IHC, IF |
FTO Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA729928 | FTO Antibody | Human | ELISA,WB,IHC |
| CSB-PA958648 | FTO Antibody | Human | ELISA,WB,IHC |
FTO Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP880154HU CSB-EP880154HU CSB-BP880154HU CSB-MP880154HU |
Recombinant Human Alpha-ketoglutarate-dependent dioxygenase FTO(FTO) | Yeast E.coli Baculovirus Mammalian cell |
2-hydroxyisobutyryl-HIST1H3A (K18) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
