G Antibody

Datasheet
Code CSB-PA14899A0Rb
See More Details Free Antibody trial simple
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Uniprot No. P03524
Image
  • Western blot
    All lanes: Rabies virus Glycoprotein G antibody at 1: 500
    Lane 1: Rabies virus antigen 1: 2
    Lane 2: Rabies virus antigen 1: 10
    Lane 3: Rabies virus antigen 1: 20
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 58 kDa
    Observed band size: 58 kDa

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Recombinant Rabies virus Glycoprotein protein (20-459AA)
Raised in Rabbit
Species Reactivity Rabies virus
Tested Applications ELISA, WB; Recommended dilution: WB:1:1000-1:5000
Relevance Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein G and thereby facilitate rabies virus entry into cells.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Glycoprotein, G
Immunogen Species Rabies virus
Research Area Others
Target Names G
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
References
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Function Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.
Subcellular Location Virion membrane, Single-pass type I membrane protein
Protein Families Lyssavirus glycoprotein family

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