G Antibody, FITC conjugated

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Code	CSB-PA14899C0Rb
Size	US$166
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Target Background

Product Details

Full Product Name

Rabbit anti-Rabies virus G Polyclonal antibody

Uniprot No.

P03524

Target Names

Alternative Names

GGlycoprotein antibody

Raised in

Rabbit

Species Reactivity

Rabies virus

Immunogen

Recombinant Rabies virus Glycoprotein protein (20-459AA)

Immunogen Species

Rabies virus

Conjugate

FITC

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Description

CUSABIO generated the Rabies virus G antibody through immunization of rabbits with the recombinant Rabies virus Glycoprotein protein (20-459AA) and final purification from rabbit antiserum by protein G. This Rabies virus G antibody is a polyclonal antibody and exists as a FITC-conjugated IgG. It can react with Rabies virus samples. Its purity is over 95%. And it is suitable for the detection of the Rabies virus G protein in the ELISA. The target protein Rabies virus G is responsible for the binding of the virus to the target cells and the fusion between viral and cell membranes during the endocytosis of the virus.

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Target Background

Function

Attaches the virus to host cellular receptor, inducing endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and cell membrane. There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind glycoprotein and thereby facilitate rabies virus entry into cells.

Subcellular Location

Virion membrane; Single-pass type I membrane protein.

Protein Families

Lyssavirus glycoprotein family

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