GPR158 Antibody, Biotin conjugated

Code CSB-PA735975LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) GPR158 Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
5330427M13Rik antibody; GP158_HUMAN antibody; GPR158 antibody; mKIAA1136 antibody; Probable G-protein coupled receptor 158 antibody; RP11-59G22.1 antibody; RP23-133B16.1 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Probable G-protein coupled receptor 158 protein (882-1003AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Orphan receptor.
Gene References into Functions
  1. Our results suggest that common ethnic-specific variation in GPR158 may influence energy expenditure (EE) in Pima Indians. rs11014566 nominally associated with measures of EE and adiposity, where the G allele associated with lower 24-h EE, lower Resting Metabolic Rate, higher BMI, and higher percent body fat. But, the association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic groups. PMID: 28476931
  2. expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression PMID: 25693195
  3. Mutation of the NLS abrogates GPR158-mediated enhancement of cell proliferation. PMID: 23451275
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 3 family
Database Links

HGNC: 23689

OMIM: 614573

KEGG: hsa:57512

STRING: 9606.ENSP00000365529

UniGene: Hs.499108

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