GPR158 Antibody

Code CSB-PA040083
Size US$119
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  • Western Blot analysis of COLO 293T HELA cells using GPR158 Polyclonal Antibody

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Product Details

Uniprot No.
Target Names
Alternative Names
5330427M13Rik antibody; GP158_HUMAN antibody; GPR158 antibody; mKIAA1136 antibody; Probable G-protein coupled receptor 158 antibody; RP11-59G22.1 antibody; RP23-133B16.1 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of Human GPR158.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
IF 1:200-1:1000
ELISA 1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Orphan receptor.
Gene References into Functions
  1. Our results suggest that common ethnic-specific variation in GPR158 may influence energy expenditure (EE) in Pima Indians. rs11014566 nominally associated with measures of EE and adiposity, where the G allele associated with lower 24-h EE, lower Resting Metabolic Rate, higher BMI, and higher percent body fat. But, the association of rs11014566 with BMI did not directionally replicate when assessed in other ethnic groups. PMID: 28476931
  2. expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression PMID: 25693195
  3. Mutation of the NLS abrogates GPR158-mediated enhancement of cell proliferation. PMID: 23451275
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 3 family
Database Links

HGNC: 23689

OMIM: 614573

KEGG: hsa:57512

STRING: 9606.ENSP00000365529

UniGene: Hs.499108

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