GRIA3 Antibody

1. Results suggest a role for GluA3 channel activity in the regulation of sleep behavior in both mice and humans. PMID: 29016847
2. miR-330-3p up-regulated the total DNA methylation in non-small cell lung cancer cells, and co-IP-demonstrated GRIA3 was directly related with DNMT1 and DNMT3A. GRIA3 is a direct target of miR-330-3p. PMID: 28629431
3. This study showed the lower GluA3 mRNA levels in pregnant women. PMID: 28284346
4. the impaired surface expression of homomeric GluA3 receptors is caused by nonproductive assembly and aggregation to which LBD residues Tyr-454 and Arg-461 strongly contribute. PMID: 26912664
5. This study demonstrated that the GRIA3 protein was altered in auditory cortex patient with schizophreia. PMID: 25433904
6. An association was observed in migraine patients with the GRIA3 single nucleotide polymorphism rs3761555. PMID: 23772601
7. The ionotrophic glutamate receptors AMPA3 and AMPA3 were decreased in hippocampus in patient with multiple sclerosis. PMID: 23595422
8. The rs557762 and the TT haplotype in the 11th haplotype block of the GRIA3 gene were associated with feelings of guilt in females. PMID: 22429480
9. the promoter methylation of the GMR2 and GMR5 genes greatly decreased the risk of schizophrenia, and the expression level of the GRM2, GRM5, and GRIA3 genes increased significantly in patients in comparison to healthy controls. PMID: 23149219
10. SNP rs687577 associated with sleep duration and depression risk in Finnish women PMID: 21966062
11. GRIA3 plays a role as a mediator of tumor progression in pancreatic cancer downstream CUX1. PMID: 20689760
12. Two variants in the regulative regions of GRIA1 (rs2195450) and GRIA3 (rs3761555) genes resulted strongly associated with MA (P = 0.00002 and P = 0.0001, respectively), but not associated with MO PMID: 20579352
13. AQP3 gene isn't the responsible gene for this pedigree with auditory neuropathy. PMID: 20564826
14. This study demonistrated that the level of metabotropic glutamate receptor 2/3 is elevated in the prefrontal cortex in patient of major depression disorder. PMID: 19945495
15. The mGlu3 receptor is located on a number of GABAergic interneurons throughout the brain. mGlu3 receptor is one of two primary mGlu receptors that modulate the function of glia. The mGlu3 receptor is present as a postsynaptic receptor as well. PMID: 19933774
16. T lymphocytes from normal individuals, an alloprimed human T cell clone, and human T leukemia (Jurkat) cells all express high levels of GluR3, identical in sequence with brain GluR3. PMID: 12682273
17. cleavage and release to the extracellular milieu of the GluR3B peptide may in principle increase its antigenicity PMID: 17202328
18. study provides the genetic and functional evidence that mutant iGluR3 with altered kinetic properties is associated with moderate cognitive impairment in humans PMID: 17989220
19. results support the involvement of genes GRIA3 and GRIK2 in antidepressant treatment-emergent suicidal ideation PMID: 18593792
20. Aberrant GRIA3 transcripts with multi-exon duplications in a family with X-linked mental retardation are reported. PMID: 19449417

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HGNC: 4573

OMIM: 300699

KEGG: hsa:2892

STRING: 9606.ENSP00000264357

UniGene: Hs.377070