GRIN2D Antibody

1. This study found that NMDAR activation, NR2D in particular, is involved in human fetal lung fibroblast proliferation and collagen production through a potential ERK1/2-mediated mechanism. PMID: 28987794
2. High GRIN2D expression is associated with colorectal cancer. PMID: 26943033
3. This study showed that the higher GluN2D mRNA level in healthy but not in depressed pregnant women as compared to non-pregnant individuals. PMID: 28284346
4. GRIN2D Recurrent De Novo Dominant Mutation Causes a Severe Epileptic Encephalopathy Treatable with NMDA Receptor Channel Blockers PMID: 27616483
5. After 7 days of chronic alcohol exposure, there are significant increases in mRNA expression of GRIN2D in cultured neurons derived from alcoholic subjects, but not in cultures from nonalcoholics. PMID: 22486492
6. Absence of truncating mutation in GRIN1 and GRIN2D genes in patients with autism spectrum disorder and schizophrenia and controls. PMID: 22833210
7. In microsatellite instable and microsatellite and chromosomally stable cancers, CIMP and BRAF/KRAS mutations are similarly distributed indicating common mechanisms of tumor initiation or progression in the molecular pathogenesis. PMID: 21915661
8. data show that the NMDAR2D was specifically expressed in cultivated keratinocytes PMID: 16328341

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HGNC: 4588

OMIM: 602717

KEGG: hsa:2906

STRING: 9606.ENSP00000263269

UniGene: Hs.445015