HSPA14 Antibody

Code CSB-PA020265
Size US$119
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Product Details

Uniprot No.
Target Names
Alternative Names
Heat shock 70 kDa protein 14 antibody; Heat shock 70kDa protein 14 antibody; Heat shock protein HSP60 antibody; Heat shock protein hsp70 related protein antibody; HSP60 antibody; HSP70 4 antibody; HSP70 like protein 1 antibody; HSP70-like protein 1 antibody; HSP70L1 antibody; HSP7E_HUMAN antibody; HSPA 14 antibody; HSPA14 antibody; MGC131990 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Synthesized peptide derived from the C-terminal region of Human HSP60.
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form
Liquid
Tested Applications
WB, IHC, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IHC 1:100-1:300
ELISA 1:40000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. In the RAC complex, binds to the nascent polypeptide chain, while DNAJC2 stimulates its ATPase activity.
Gene References into Functions
  1. TLR4 is a key receptor mediating the interaction of Hsp70L1 with DCs and subsequently enhancing the induction of Th1 immune response by Hsp70L1/antigen fusion protein PMID: 21730052
  2. a novel pathway (NBS1-HSF4b-HSPA4/HSPA14 axis) to induce migration, invasion, and transformation, suggesting the activation of multiple signaling events induced by NBS1 overexpression PMID: 21208456
  3. results demonstrate that Hsp70L1 has enhanced Th1 polarizing and adjuvant properties, which appear to be mediated via activation of dendritic cells PMID: 14592822
Subcellular Location
Cytoplasm, cytosol.
Protein Families
Heat shock protein 70 family
Database Links

HGNC: 29526

OMIM: 610369

KEGG: hsa:51182

STRING: 9606.ENSP00000367623

UniGene: Hs.534169

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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