HTR1F Antibody

Datasheet

Code	CSB-PA004147
Size	US$167
Image	Western Blot analysis of COS7 cells using SR-1F Polyclonal Antibody
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Product Details
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Target Data

Product Details

Uniprot No.

P30939

Target Names

HTR1F

Alternative Names

HTR1F antibody; HTR1EL5-hydroxytryptamine receptor 1F antibody; 5-HT-1F antibody; 5-HT1F antibody; Serotonin receptor 1F antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat,Monkey

Immunogen

Synthesized peptide derived from the Internal region of Human SR-1F.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IF	1:200-1:1000
ELISA	1:40000

Protocols

Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Target Data

Function	G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various alkaloids and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity.
Gene References into Functions	Supporting this model, pharmacological activation of 5-HT1F receptors reduces glucagon secretion and has hypoglycemic effects in diabetic mice. Thus, modulation of serotonin signaling in the islet represents a drug intervention opportunity PMID: 28009296 5-HT6 show no striking effects on executive function in the Chinese Han population. PMID: 21457069
Subcellular Location	Cell membrane, Multi-pass membrane protein
Protein Families	G-protein coupled receptor 1 family
Database Links	HGNC: 5292 OMIM: 182134 KEGG: hsa:3355 STRING: 9606.ENSP00000322924 UniGene: Hs.248136