INTS10 Antibody

Datasheet

Code	CSB-PA011758ESR1HU
Size	US$166
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Image	Western blot All lanes: INTS10 antibody at 4.35μg/ml Lane 1: Mouse kidney tissue Lane 2: Rat gonadal tissue Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 82 kDa Observed band size: 82 kDa Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA011758ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA011758ESR1HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) INTS10 Polyclonal antibody

Uniprot No.

Q9NVR2

Target Names

INTS10

Alternative Names

INTS10 antibody; C8orf35 antibody; Integrator complex subunit 10 antibody; Int10 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Integrator complex subunit 10 protein (451-710AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). May be not involved in the recruitment of cytoplasmic dynein to the nuclear envelope by different components of the INT complex.

Gene References into Functions

Genome-wide association study in Chinise population highlights a novel antiviral gene INTS10 at 8p21.3 in the clearance of HBV infection. INST10 suppresses HBV replication via IRF3 in liver cells. PMID: 27244555
Using a 7,781-sample pan-cancer dataset, we first confirmed this in POLR2A are known to confer elevated sensitivity to pharmacological suppression.hese include the POLR2A interacting protein INTS10 as well as genes involved in mRNA splicing, nonsense-mediated mRNA PMID: 28027311

Subcellular Location

Nucleus.

Protein Families

Integrator subunit 10 family

Database Links

HGNC: 25548

OMIM: 611353

KEGG: hsa:55174

STRING: 9606.ENSP00000381064

UniGene: Hs.512627

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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