JCHAIN Antibody

Code CSB-PA011337DSR1HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human tonsil tissue using CSB-PA011337DSR1HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA011337DSR1HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) JCHAIN Polyclonal antibody
Uniprot No.
Target Names
JCHAIN
Alternative Names
IGCJ antibody; IGJ_HUMAN antibody; Immunoglobulin J chain antibody; Immunoglobulin J polypeptide linker protein for immunoglobulin alpha and mu polypeptides antibody; immunoglobulin joining chain antibody; JCH antibody; JCHAIN antibody; Joining chain of multimeric IgA and IgM antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Immunoglobulin J chain protein (23-159AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces dimers and/or larger polymers. It also helps to bind these immunoglobulins to secretory component.
Gene References into Functions
  1. TLR2 ligands induce CCR9 and CCR10 expression by circulating B-cells and increase their chemotaxis. TLR2 stimulation also induced J chain and IgA production demonstrating the induction of mucosal-like antibody secreting cells. PMID: 20947433
Subcellular Location
Secreted.
Database Links

HGNC: 5713

OMIM: 147790

KEGG: hsa:3512

STRING: 9606.ENSP00000254801

UniGene: Hs.643431

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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