KCNK13 Antibody

Code CSB-PA940234
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA940234(KCNK13 Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: ×200)
  • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane: Mouse lung tissue, Primary antibody: CSB-PA940234(KCNK13 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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Product Details

Uniprot No.
Target Names
KCNK13
Alternative Names
KCNK13; Potassium channel subfamily K member 13; Tandem pore domain halothane-inhibited potassium channel 1; THIK-1
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human KCNK13
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,WB,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Potassium channel displaying weak inward rectification in symmetrical K(+) solution.
Gene References into Functions
  1. Dysregulation of a potassium channel, THIK-1, targeted by caspase-8, accelerates cell shrinkage. PMID: 27566292
  2. In cell and tissues co-expressing THIK1 and THIK2, heterodimeric channels may contribute to cell excitability. PMID: 25148687
  3. expression in cell hypoxia PMID: 16683720
  4. THIK-1 and THIK-2 are abundantly expressed in the proximal and distal nephron of the mammalian kidney. PMID: 18209473
Subcellular Location
Membrane; Multi-pass membrane protein.
Protein Families
Two pore domain potassium channel (TC 1.A.1.8) family
Database Links

HGNC: 6275

OMIM: 607367

KEGG: hsa:56659

STRING: 9606.ENSP00000282146

UniGene: Hs.510191

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