LDHC Antibody

Code CSB-PA012844LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western Blot
    Positive WB detected in: NIH/3T3 whole cell lysate, HepG2 whole cell lysate, Mouse brain tissue, Mouse heart tissue, Mouse lung tissue, Mouse thymus tissue, Rat liver tissue
    All lanes: LDHC antibody at 3.2μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 37 kDa
    Observed band size: 37 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA012844LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human small intestine tissue using CSB-PA012844LA01HU at dilution of 1:100

  • Immunofluorescent analysis of Hela cells using CSB-PA012844LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) LDHC Polyclonal antibody
Uniprot No. P07864
Target Names LDHC
Alternative Names Cancer/testis antigen 32 antibody; CT32 antibody; EC 1.1.1.27 antibody; L lactate dehydrogenase C chain antibody; L-lactate dehydrogenase C chain antibody; Lactate Dehydrogenase C antibody; Lactate dehydrogenase c variant 1 antibody; Lactate dehydrogenase c variant 3 antibody; Lactate dehydrogenase c variant 4 antibody; Lactate dehydrogenase C4 antibody; LDH C antibody; LDH testis subunit antibody; LDH X antibody; LDH-C antibody; LDH-X antibody; LDH3 antibody; ldhc antibody; LDHC_HUMAN antibody; LDHX antibody; MGC111073 antibody
Raised in Rabbit
Species Reactivity Human, Mouse, Rat
Immunogen Recombinant Human L-lactate dehydrogenase C chain protein (2-332AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
(From Uniprot)
Possible role in sperm motility.
Gene References into Functions
  1. Lactate dehydrogenase C may act as a novel biomarker for renal cell carcinoma progression and a potential therapeutic target for the treatment of renal cell carcinoma. PMID: 28351304
  2. three uniquely identified proteins (CDK6 , galectin-3-binding protein and LDH C) were found, which show tight connection with prostate cancer and presence of all of them was previously linked to certain aspects of prostate cancer PMID: 26503549
  3. Down-regulated LDH-C4 expression is significantly correlated with lowered enzyme activity in human spermatozoa. PMID: 25795631
  4. This is the first report to show a positive correlation between LDH-3 and hemolytic parameters in sickle cell anemia. PMID: 26069337
  5. LDH3 was increased in essential thrombocythemia. This isoenzymatic pattern could be expression of a metabolic adaptation. PMID: 17178662
  6. LDH3 is a supporting diagnostic marker in cases of chronic tuberculosis. PMID: 17935709
  7. hLdhc expression in cancer cells was regulated by transcription factor Sp1 and CREB and promoter CGI methylation PMID: 18930904

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Subcellular Location Cytoplasm
Protein Families LDH/MDH superfamily, LDH family
Database Links

HGNC: 6544

OMIM: 150150

KEGG: hsa:3948

STRING: 9606.ENSP00000280704

UniGene: Hs.654377

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