Code | CSB-RA886298A0HU |
Size | US$210 |
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Application | Recommended Dilution |
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FC | 1:50-1:200 |
The generation of the LDHC recombinant monoclonal antibody involves a genetic engineering process that includes cloning and expression of the gene responsible for the LDHC monoclonal antibody. To generate the LDHC monoclonal antibody, a synthesized peptide derived from human LDHC protein was used as the immunogen. The LDHC recombinant monoclonal antibody was purified using affinity chromatography to ensure high purity. It specifically recognizes and binds to the human MAS1L protein. The quality and specificity of the LDHC recombinant monoclonal antibody have been confirmed through two applications ELISA and FC.
LDHC is an enzyme that plays a crucial role in the anaerobic metabolism of glucose. It catalyzes the reversible conversion of pyruvate to lactate, producing NAD+ from NADH. This process is important in energy production during periods of high-intensity exercise when oxygen availability is limited. LDHC is predominantly expressed in the testis, where it is essential for the process of spermatogenesis. However, it is also expressed in other tissues, such as muscle and brain, where it may have other functions beyond energy metabolism. Mutations in the LDHC gene have been associated with male infertility.
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