MAFF Antibody

Datasheet

Code	CSB-PA978613
Size	US$166
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Image	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: CSB-PA978613(MAFF Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details
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Target Background

Product Details

Uniprot No.

Q9ULX9

Target Names

MAFF

Alternative Names

Avian musculoaponeurotic fibrosarcoma virus (v maf) AS42 oncogene, protein F antibody; CTA 447C4.1 antibody; hMafF antibody; MAFF antibody; MAFF_HUMAN antibody; OTTHUMP00000199299 antibody; Transcription factor MafF antibody; U MAF antibody; U-Maf antibody; V maf avian musculoaponeurotic fibrosarcoma oncogene family, protein F antibody; V maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian) antibody; V maf musculoaponeurotic fibrosarcoma oncogene homolog F antibody; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse

Immunogen

Synthetic peptide of Human MAFF

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins, such as NFE2L1/NRF1, and recruiting them to specific DNA-binding sites. Interacts with the upstream promoter region of the oxytocin receptor gene. May be a transcriptional enhancer in the up-regulation of the oxytocin receptor gene at parturition.

Gene References into Functions

MAF genes have different levels of biological and genetic relevance. Besides, MAFF and MAFG could be associated with the susceptibility to develop CML. PMID: 24118457
MafF/NFE2 hetrodimers act as weak transcriptional activators, and, in particular, are able to stimulate activity of the GCS1 promoter. PMID: 12490281
In myometrial cells we observed an important induction by interleukin 1 beta and a weaker upregulation by tumor necrosis factor, whereas interleukin 6 treatment had no effect. PMID: 16371591
Expression of hMafF or MIP alone did not alter basal reporter transcription activity, whereas co-expression of hMafF and MIP activated transcription efficiently. PMID: 16549056
Only in the presence of both MIP and hMafF could the nUS2-pLacZi reporter in yeast genome be activated. PMID: 19723544

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Subcellular Location

Nucleus.

Protein Families

BZIP family, Maf subfamily

Tissue Specificity

Expressed in the term myometrium and kidney.

Database Links

HGNC: 6780

OMIM: 604877

KEGG: hsa:23764

STRING: 9606.ENSP00000345393

UniGene: Hs.517617

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Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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