MAGEB2 Antibody

Datasheet

Code	CSB-PA992599
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA992599(MAGEB2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
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Product Details
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Target Background

Product Details

Uniprot No.

O15479

Target Names

MAGEB2

Alternative Names

MAGEB2Melanoma-associated antigen B2 antibody; Cancer/testis antigen 3.2 antibody; CT3.2 antibody; DSS-AHC critical interval MAGE superfamily 6 antibody; DAM6 antibody; MAGE XP-2 antigen antibody; MAGE-B2 antigen antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human MAGEB2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

May enhance ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases. Proposed to act through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex.

Gene References into Functions

MAGEB2 can be aberrantly demethylated and expressed in malignant peripheral nerve sheath tumors. Conversely, the gene may not be demethylated in any types of neurofibroma, suggesting that the demethylation does not occur before malignant transformation. PMID: 26642794
MageB2 counteracts E2F inhibition by ribosomal proteins independently of Mdm2 expression PMID: 26468294
we identified MAGEB2 as activated by promoter demethylation in HNSCCand demonstrates growth promoting effects in a minimally transformed oral keratinocyte cell line. PMID: 23029077
Valproic acid causes a change in acetylation of this gene. PMID: 17012225

Tissue Specificity

Expressed in testis and placenta, and in a significant fraction of tumors of various histologic types.

Database Links

HGNC: 6809

OMIM: 300098

KEGG: hsa:4113

STRING: 9606.ENSP00000368273

UniGene: Hs.113824

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Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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