MAP3K13 Antibody, Biotin conjugated

Code CSB-PA013421LD01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MAP3K13 Polyclonal antibody
Uniprot No.
Target Names
MAP3K13
Alternative Names
EC 2.7.11.25 antibody; Leucine zipper bearing kinase antibody; Leucine zipper-bearing kinase antibody; LZK antibody; M3K13_HUMAN antibody; MAP3K13 antibody; MEKK13 antibody; MGC133196 antibody; Mitogen activated protein kinase kinase kinase 13 antibody; Mitogen-activated protein kinase kinase kinase 13 antibody; Mixed lineage kinase antibody; MLK antibody; OTTHUMP00000210397 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mitogen-activated protein kinase kinase kinase 13 protein (506-835AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Biotin
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.
Gene References into Functions
  1. Data indicate that miR-206's effect on Myc was mediated through MAP3K13. PMID: 26918941
  2. Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27. PMID: 12186766
Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Protein Families
Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily
Tissue Specificity
Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.
Database Links

HGNC: 6852

OMIM: 604915

KEGG: hsa:9175

STRING: 9606.ENSP00000265026

UniGene: Hs.591306

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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