MAP3K13 Antibody

Datasheet

Code	CSB-PA029472
Size	US$297
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Image	Western blot analysis of extracts from HeLa cells, HUVEC cells and HepG2 cells, using M3K13 antibody.
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MAP3K13 Polyclonal antibody

Uniprot No.

O43283

Target Names

MAP3K13

Alternative Names

EC 2.7.11.25 antibody; Leucine zipper bearing kinase antibody; Leucine zipper-bearing kinase antibody; LZK antibody; M3K13_HUMAN antibody; MAP3K13 antibody; MEKK13 antibody; MGC133196 antibody; Mitogen activated protein kinase kinase kinase 13 antibody; Mitogen-activated protein kinase kinase kinase 13 antibody; Mixed lineage kinase antibody; MLK antibody; OTTHUMP00000210397 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthesized peptide derived from internal of Human M3K13.

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Tested Applications

ELISA,WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:3000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Gene References into Functions

Data indicate that miR-206's effect on Myc was mediated through MAP3K13. PMID: 26918941
Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27. PMID: 12186766

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein.

Protein Families

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily

Tissue Specificity

Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.

Database Links

HGNC: 6852

OMIM: 604915

KEGG: hsa:9175

STRING: 9606.ENSP00000265026

UniGene: Hs.591306

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

MAPK signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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