MAP3K13 Antibody

Datasheet

Code	CSB-PA013421LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: Rat liver tissue, Rat lung tissue, Mouse liver tissue, Mouse stomach tissue All lanes: MAP3K13 antibody at 3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 109, 18, 93, 86, 15 kDa Observed band size: 109 kDa Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA013421LA01HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MAP3K13 Polyclonal antibody

Uniprot No.

O43283

Target Names

MAP3K13

Alternative Names

EC 2.7.11.25 antibody; Leucine zipper bearing kinase antibody; Leucine zipper-bearing kinase antibody; LZK antibody; M3K13_HUMAN antibody; MAP3K13 antibody; MEKK13 antibody; MGC133196 antibody; Mitogen activated protein kinase kinase kinase 13 antibody; Mitogen-activated protein kinase kinase kinase 13 antibody; Mixed lineage kinase antibody; MLK antibody; OTTHUMP00000210397 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant Human Mitogen-activated protein kinase kinase kinase 13 protein (506-835AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The MAP3K13 Antibody (Product code: CSB-PA013421LA01HU) is Non-conjugated. For MAP3K13 Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA013421LB01HU	MAP3K13 Antibody, HRP conjugated	ELISA
FITC	CSB-PA013421LC01HU	MAP3K13 Antibody, FITC conjugated
Biotin	CSB-PA013421LD01HU	MAP3K13 Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:5000
IHC	1:20-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. Acts synergistically with PRDX3 to regulate the activation of NF-kappa-B in the cytosol. This activation is kinase-dependent and involves activating the IKK complex, the IKBKB-containing complex that phosphorylates inhibitors of NF-kappa-B.

Gene References into Functions

Data indicate that miR-206's effect on Myc was mediated through MAP3K13. PMID: 26918941
Chromosomal localization studies involving FISH mapping demonstrated that the human LZK gene is located at 3q27. PMID: 12186766

Subcellular Location

Cytoplasm. Membrane; Peripheral membrane protein.

Protein Families

Protein kinase superfamily, STE Ser/Thr protein kinase family, MAP kinase kinase kinase subfamily

Tissue Specificity

Expressed in the adult brain, liver, placenta and pancreas, with expression strongest in the pancreas.

Database Links

HGNC: 6852

OMIM: 604915

KEGG: hsa:9175

STRING: 9606.ENSP00000265026

UniGene: Hs.591306

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

MAPK signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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