MNT Antibody

Code CSB-PA107744
Size US$297
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  • Western blot analysis of extracts from A549 cells, using MNT antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MNT Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
bHLHd3 antibody; Class D basic helix-loop-helix protein 3 antibody; MAD6 antibody; MAX binding protein antibody; Max binding protein MNT antibody; MAX network transcriptional repressor antibody; Max-binding protein MNT antibody; Mnt antibody; MNT_HUMAN antibody; MXD6 antibody; Myc antagonist MNT antibody; Protein ROX antibody; ROX antibody
Raised in
Species Reactivity
Synthesized peptide derived from internal of Human MNT.
Immunogen Species
Homo sapiens (Human)
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
It differs from different batches. Please contact us to confirm it.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Binds DNA as a heterodimer with MAX and represses transcription. Binds to the canonical E box sequence 5'-CACGTG-3' and, with higher affinity, to 5'-CACGCG-3'.
Gene References into Functions
  1. In vitro, uremia induced dysregulation of DNA methylation in differentiating monocytes, which affected several transcription regulators important for monocyte differentiation (e.g., FLT3, HDAC1, MNT) and led to enhanced generation of intermediate monocytes. PMID: 27018948
  2. The data demonstrate that the balance between c-Myc and Mnt activity determines the transcriptional outcome of the hTERT promoter by modulation of the chromatin architecture. PMID: 23860446
  3. The results suggest that MNT, via interaction with Nck1, inhibits hepatoma cell migration. PMID: 22964333
  4. downregulation MYCN was reflected in a decreased MYCN/Max DNA-binding activity while the Mnt/Max binding did not change during differentiation PMID: 15258910
  5. Serum stimulation of quiescent cells results in phosphorylation of Mnt and disruption of the critical Mnt-mSin3-HDAC1 interaction. This in turn leads to increased expression of the Myc/Mnt target gene cyclin D2. Review. PMID: 17419941

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Subcellular Location
Database Links

HGNC: 7188

OMIM: 603039

KEGG: hsa:4335

STRING: 9606.ENSP00000174618

UniGene: Hs.626579

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