MOB1B Antibody

Code CSB-PA970943
Size US$297
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  • Western blot analysis of extracts from 293 cells, COS-7 cells and HUVEC cells all treated with IFN (2500U/ml, 30mins), using MOL1A antibody.
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MOB1B Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
MATS 2 antibody; MATS2 antibody; MGC33910 antibody; Mob 1A antibody; Mob 1B antibody; MOB 4A antibody; MOB kinase activator 1B antibody; Mob1 homolog 1A antibody; MOB1 Mps One Binder homolog B antibody; MOB1 Mps one binder kinase activator like 1A antibody; Mob1A antibody; Mob1B antibody; MOBKL 1A antibody; MOBKL1A antibody; MOL1A_HUMAN antibody; Mps one binder kinase activator like 1A antibody; Mps one binder kinase activator-like 1A antibody; Protein Mob4A antibody
Raised in
Species Reactivity
Synthesized peptide derived from internal of Human MOL1A.
Immunogen Species
Homo sapiens (Human)
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
It differs from different batches. Please contact us to confirm it.
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Tested Applications
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:3000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Phosphorylation of YAP1 by LATS1/2 inhibits its translocation into the nucleus to regulate cellular genes important for cell proliferation, cell death, and cell migration. Stimulates the kinase activity of STK38L.
Subcellular Location
Cytoplasm. Nucleus.
Protein Families
MOB1/phocein family
Tissue Specificity
Adrenal gland, bone marrow, brain, lung, placenta, prostate, salivary gland, skeletal muscle, testis, thymus, thyroid gland, uterus, colon with mucosa, fetal brain and fetal liver.
Database Links

HGNC: 29801

OMIM: 609282

KEGG: hsa:92597

STRING: 9606.ENSP00000310189

UniGene: Hs.691454

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