MOB kinase activator 1B is a protein in humans that is encoded by MOB1B gene. Activator of LATS1/2 in the Hippo signaling pathway which plays a pivotal role in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein STK3/MST2 and STK4/MST1, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ.

MOB1B Antibodies

MOB1B Antibodies for Homo sapiens (Human)

MOB1B Antibodies for Arabidopsis thaliana (Mouse-ear cress)

MOB1B Proteins

MOB1B Proteins for Homo sapiens (Human)

MOB1B Proteins for Mus musculus (Mouse)

MOB1B Proteins for Arabidopsis thaliana (Mouse-ear cress)


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