MRGPRX3 Antibody

Code CSB-PA850382LA01HU
Size US$166
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  • Immunofluorescent analysis of HepG2 cells using CSB-PA850382LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MRGPRX3 Polyclonal antibody
Uniprot No.
Target Names
MRGPRX3
Alternative Names
G protein coupled receptor SNSR1 antibody; G protein coupled receptor SNSR2 antibody; G protein-coupled receptor MRGX 3 antibody; G protein-coupled receptor MRGX3 antibody; GPCR antibody; Mas related GPCR member X3 antibody; Mas-related G protein coupled MRGX 3 antibody; Mas-related G protein coupled MRGX3 antibody; Mas-related G-protein coupled receptor member X3 antibody; MAS-related GPR, member X3 antibody; MRGPRX3 antibody; MRGX3 antibody; MRGX3_HUMAN antibody; Sensory neuron-specific G-protein coupled receptor 1 antibody; Sensory neuron-specific G-protein coupled receptor 1/2 antibody; SNSR1 antibody; SNSR2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mas-related G-protein coupled receptor member X3 protein (276-322AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The MRGPRX3 Antibody (Product code: CSB-PA850382LA01HU) is Non-conjugated. For MRGPRX3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA850382LB01HU MRGPRX3 Antibody, HRP conjugated ELISA
FITC CSB-PA850382LC01HU MRGPRX3 Antibody, FITC conjugated
Biotin CSB-PA850382LD01HU MRGPRX3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, IF
Recommended Dilution
Application Recommended Dilution
IF 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.
Gene References into Functions
  1. Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID: 29408502
  2. Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID: 28189739
  3. overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID: 15809047
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family, Mas subfamily
Tissue Specificity
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
Database Links

HGNC: 17980

OMIM: 607229

KEGG: hsa:117195

STRING: 9606.ENSP00000379571

UniGene: Hs.380177

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