MRGPRX3 Antibody

Datasheet

Code	CSB-PA006889
Size	US$119
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Image	Western Blot analysis of K562 cells using MRGX3 Polyclonal Antibody
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q96LB0

Target Names

MRGPRX3

Alternative Names

G protein coupled receptor SNSR1 antibody; G protein coupled receptor SNSR2 antibody; G protein-coupled receptor MRGX 3 antibody; G protein-coupled receptor MRGX3 antibody; GPCR antibody; Mas related GPCR member X3 antibody; Mas-related G protein coupled MRGX 3 antibody; Mas-related G protein coupled MRGX3 antibody; Mas-related G-protein coupled receptor member X3 antibody; MAS-related GPR, member X3 antibody; MRGPRX3 antibody; MRGX3 antibody; MRGX3_HUMAN antibody; Sensory neuron-specific G-protein coupled receptor 1 antibody; Sensory neuron-specific G-protein coupled receptor 1/2 antibody; SNSR1 antibody; SNSR2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthesized peptide derived from the Internal region of Human MRGX3.

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

WB, IF, ELISA

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000
IF	1:200-1:1000
ELISA	1:10000

Protocols

Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

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Target Background

Function

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.

Gene References into Functions

Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID: 29408502
Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID: 28189739
overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID: 15809047

Subcellular Location

Cell membrane; Multi-pass membrane protein.

Protein Families

G-protein coupled receptor 1 family, Mas subfamily

Tissue Specificity

Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

Database Links

HGNC: 17980

OMIM: 607229

KEGG: hsa:117195

STRING: 9606.ENSP00000379571

UniGene: Hs.380177

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

G protein coupled receptor signaling pathway Target Therapy

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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