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MRGPRX3 Antibody, HRP conjugated

Datasheet
Code CSB-PA850382LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MRGPRX3 Polyclonal antibody
Uniprot No.
Q96LB0
Target Names
MRGPRX3
Alternative Names
G protein coupled receptor SNSR1 antibody; G protein coupled receptor SNSR2 antibody; G protein-coupled receptor MRGX 3 antibody; G protein-coupled receptor MRGX3 antibody; GPCR antibody; Mas related GPCR member X3 antibody; Mas-related G protein coupled MRGX 3 antibody; Mas-related G protein coupled MRGX3 antibody; Mas-related G-protein coupled receptor member X3 antibody; MAS-related GPR, member X3 antibody; MRGPRX3 antibody; MRGX3 antibody; MRGX3_HUMAN antibody; Sensory neuron-specific G-protein coupled receptor 1 antibody; Sensory neuron-specific G-protein coupled receptor 1/2 antibody; SNSR1 antibody; SNSR2 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Mas-related G-protein coupled receptor member X3 protein (276-322AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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MRGPRX3 Antibodies

MRGPRX3 Proteins

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Target Background

Function
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins.
Gene References into Functions
  1. Our data demonstrate that GPR182 is an endothelial subtype-specific marker for human sinusoidal EC of the liver, spleen, lymph node and bone marrow. In addition, we provide evidence for GPR182-dependent downstream signaling via ERK and SRF pathways that may be involved in regulating endothelial subtype-specific sinusoidal differentiation and sinusoidal functions such as permeability. PMID: 29408502
  2. Potential of GPCRs to modulate MAPK and mTOR pathways in different stages of the neurodegenerative disease. PMID: 28189739
  3. overexpression of the human MrgX3 gene causes a disturbance of the normal cell-differentiation process PMID: 15809047
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Protein Families
G-protein coupled receptor 1 family, Mas subfamily
Tissue Specificity
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
Database Links

HGNC: 17980

OMIM: 607229

KEGG: hsa:117195

STRING: 9606.ENSP00000379571

UniGene: Hs.380177

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Related pathways
G protein coupled receptor signaling pathway Target Therapy
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