MYBPC2 Antibody

Datasheet

Code	CSB-PA618884ESR2HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA618884ESR2HU at dilution of 1:100
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Product Details
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Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) MYBPC2 Polyclonal antibody

Uniprot No.

Q14324

Target Names

MYBPC2

Alternative Names

C protein, skeletal muscle fast isoform antibody; C-protein antibody; Fast MyBP C antibody; Fast MyBP-C antibody; MGC163408 antibody; MYBPC antibody; Mybpc2 antibody; MYBPCF antibody; Myosin binding protein C, fast type antibody; Myosin-binding protein C, fast-type antibody; MYPC2_HUMAN antibody; skeletal muscle fast isoform antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Myosin-binding protein C, fast-type protein (912-1141AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.

Gene References into Functions

the mean methylation level of CpGs was significantly higher in MYBPC3 than MYBPC2. PMID: 20740642
The patients with a frameshift deletion mutation of MyBPC may develop LV systolic dysfunction and suffer from cardiovascular events through mid-life and beyond. PMID: 20605413
Identification of interactions between domains of Myosin binding protein-C that are modulated by hypertrophic cardiomyopathy missense mutations. PMID: 12386147
the CD-loop is a natively unfolded sequence with a likely coupling between folding and ligand binding. PMID: 17876814
Role and quaternary structure of MyBPC in skeletal muscle. PMID: 18201573
The distribution of MyBP-C in the A-bands of cardiac and skeletal muscles and compare this to the A-band structure in cardiac muscle of MyBP-C-deficient mice, was investigated. PMID: 18817784

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Protein Families

Immunoglobulin superfamily, MyBP family

Database Links

HGNC: 7550

OMIM: 160793

KEGG: hsa:4606

STRING: 9606.ENSP00000350332

UniGene: Hs.85937

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Antibody Service

Protein Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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