MYBPC2 Antibody, HRP conjugated

Code CSB-PA618884LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) MYBPC2 Polyclonal antibody
Uniprot No.
Target Names
MYBPC2
Alternative Names
C protein, skeletal muscle fast isoform antibody; C-protein antibody; Fast MyBP C antibody; Fast MyBP-C antibody; MGC163408 antibody; MYBPC antibody; Mybpc2 antibody; MYBPCF antibody; Myosin binding protein C, fast type antibody; Myosin-binding protein C, fast-type antibody; MYPC2_HUMAN antibody; skeletal muscle fast isoform antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Myosin-binding protein C, fast-type protein (739-1141AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role.
Gene References into Functions
  1. the mean methylation level of CpGs was significantly higher in MYBPC3 than MYBPC2. PMID: 20740642
  2. The patients with a frameshift deletion mutation of MyBPC may develop LV systolic dysfunction and suffer from cardiovascular events through mid-life and beyond. PMID: 20605413
  3. Identification of interactions between domains of Myosin binding protein-C that are modulated by hypertrophic cardiomyopathy missense mutations. PMID: 12386147
  4. the CD-loop is a natively unfolded sequence with a likely coupling between folding and ligand binding. PMID: 17876814
  5. Role and quaternary structure of MyBPC in skeletal muscle. PMID: 18201573
  6. The distribution of MyBP-C in the A-bands of cardiac and skeletal muscles and compare this to the A-band structure in cardiac muscle of MyBP-C-deficient mice, was investigated. PMID: 18817784

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Protein Families
Immunoglobulin superfamily, MyBP family
Database Links

HGNC: 7550

OMIM: 160793

KEGG: hsa:4606

STRING: 9606.ENSP00000350332

UniGene: Hs.85937

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