MYLK2 Antibody

Code CSB-PA189164
Size US$166
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  • Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane: Mouse muscle tissue, Primary antibody: CSB-PA189164(MYLK2 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 minutes
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Product Details

Uniprot No.
Target Names
Alternative Names
KMLC antibody; MLCK antibody; MLCK, skeletal/cardiac antibody; MLCK2 antibody; MYLK 2 antibody; MYLK2 antibody; MYLK2_HUMAN antibody; Myosin light chain kinase 2 antibody; Myosin light chain kinase 2 skeletal muscle antibody; Myosin light chain kinase 2 skeletal/cardiac muscle antibody; MYOSIN LIGHT POLYPEPTIDE KINASE antibody; Myosin light polypeptide kinase, skeletal/cardiac antibody; Skeletal muscle myosin light chain kinase antibody; Skeletal myosin light chain kinase antibody; skeletal/cardiac muscle antibody; skMLCK antibody
Raised in
Species Reactivity
Fusion protein of Human MYLK2
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen affinity purification
It differs from different batches. Please contact us to confirm it.
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Tested Applications
Recommended Dilution
Application Recommended Dilution
ELISA 1:1000-1:2000
WB 1:200-1:1000
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain.
Gene References into Functions
  1. the P2X1-ERK2-Myosin Light Chain Kinase axis contributes to collagen-induced platelet activation by enhancing platelet degranulation PMID: 14500714
  2. These data suggest that the kinase domain of MYLK2 is rarely mutated in common human carcinomas and that it does not play a dominant role in cancer pathogenesis. PMID: 16448786
  3. MYLK gene is a risk factor for the development of acute lung injuries. PMID: 18828194
  4. Data show that that the prototypical CaM target sequence skMLCK, a fragment from skeletal muscle myosin light chain kinase, binds to CaM in a highly cooperative way, while only a lower degree of interdomain binding cooperativity emerges for CaMKK. PMID: 19667195
Involvement in disease
Cardiomyopathy, familial hypertrophic (CMH)
Subcellular Location
Cytoplasm. Note=Colocalizes with phosphorylated myosin light chain (RLCP) at filaments of the myofibrils.
Protein Families
Protein kinase superfamily, CAMK Ser/Thr protein kinase family
Tissue Specificity
Heart and skeletal muscles. Increased expression in the apical tissue compared to the interventricular septal tissue.
Database Links

HGNC: 16243

OMIM: 192600

KEGG: hsa:85366

STRING: 9606.ENSP00000365152

UniGene: Hs.86092

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