Maged1 Antibody

1. Both transient and stable expression of Necdin induced osteoblast-specific markers in an osteogenic cell line through formation of a complex with melanoma-associated antigen D1 (MAGE-D1) and promoter activation. PMID: 28528976
2. MAGED1 as a novel regulator of osteoblastogenesis, osteoclastogenesis, and bone remodeling in a mouse model PMID: 26272363
3. Maged1 deficiency prevented the interaction of Maged1 with cAMP response element-binding protein (CREB). PMID: 24700102
4. NRAGE is a potent regulator of proliferation and odontoblastic differentiation of mouse dental pulp cells, which might be via the NF-kappaB signalling pathway. PMID: 25736627
5. Show Ror2 expression is higher in highly metastatic cell line than in low metastatic variant cell line. Our data show that Ror2 is a potential factor in the tumorigenesis and metastasis in a Src-dependent manner that is negatively regulated by NRAGE. PMID: 23142633
6. We conclude that Maged1 is required for OT processing or stability. A decrease in mature OT levels in Maged1 mutants affects social interactions and possibly other behavioral processes PMID: 22865874
7. Maged1 is involved in osteoblast proliferation and differentiation. Mice deficient in Maged1 protein had decreased bone mineral density (BMD) PMID: 23300464
8. the present findings suggest a novel role for MAGE-D1 in depressive behaviors: modulating SERT ubiquitylation. PMID: 22457503
9. XIAP-TAB1-TAK1 complex is dependent on NRAGE for IKK-alpha/beta phosphorylation and NF-kappaB activation. PMID: 21789165
10. MAGED1 binds to nuclear receptor RORalpha to bring about positive and negative effects on core clock genes of Bmal1, Rev-erbalpha and E4bp4 expression through the Rev-Erbalpha/ROR responsive elements (RORE). PMID: 20300063
11. NRAGE induces NF-kappaB activation and MIF expression in P19 cells PMID: 20100315
12. MHD2 of NRAGE was not necessary for BMP-induced p38MAPK activation or caspase-mediated apoptosis. PMID: 19937275
13. roles for NRAGE as a mediator of precursor apoptosis and a repressor of cell cycle progression in neural development PMID: 12204258
14. receptor tyrosine kinase-like orphan receptor 2(Ror2) sequesters Dlxin-1 in membranous compartments, thereby affecting the transcriptional function of Mhomeobox, msh-like 2(msx2) PMID: 12754255
15. The expression pattern of Maged1 roughly summarizes that of Maged2 and Maged3 PMID: 15162511
16. necdin and MAGE-D1 cooperate to modulate the function of Dlx/Msx homeodomain proteins in cellular differentiation PMID: 15272023
17. Our results suggest that interaction of cytosolic PrP and NRAGE could affect neuronal viability. PMID: 15911347
18. NRAGE as an integral component in bone morphogenetic proteins signaling and clarify its role during neural progenitor development PMID: 16107717
19. NRAGE plays an important role in apoptotic-signaling in vivo. PMID: 18772898
20. NRAGE might have multiple roles during renal branching morphogenesis through association with both the BMP and GDNF signaling pathways. PMID: 19268530
21. The netrin receptor UNC5H1 induces apoptosis through and interaction with NRAGE. PMID: 12598531

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KEGG: mmu:94275

STRING: 10090.ENSMUSP00000026142

UniGene: Mm.27578