NGFR Antibody

Datasheet
Code CSB-PA003448
Size US$167
Image
  • Western Blot analysis of HepG2 cells using NGFR p75 Polyclonal Antibody
  • Western Blot analysis of K562 cells using NGFR p75 Polyclonal Antibody

Product Details

Uniprot No. P08138
Target Names NGFR
Alternative Names NGFR; TNFRSF16; Tumor necrosis factor receptor superfamily member 16; Gp80-LNGFR; Low affinity neurotrophin receptor p75NTR; Low-affinity nerve growth factor receptor; NGF receptor; p75 ICD; CD antigen CD271
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of Human NGFR p75.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, IF, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
IF 1:200-1:1000
ELISA 1:40000
Protocols Western Blotting(WB) Protocol
Immunofluorescence (IF) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Citations

Lobular architecture of human adipose tissue defines the niche and fate of progenitor cells. Esteve D,NATURE COMMUNICATIONS,2019

Applications: IF
Antibody dilution factor: 1: 100
Review: Representative images of CYTOKERATINS (green) and CD271 (red) immunostainings on the SC and VS lobule septa (n=3). Nuclei are stained with DAPI (blue). Scale bars: 100µm.
PMID: 31186409

Target Data

Function Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Subcellular Location Membrane, Single-pass type I membrane protein
Database Links

HGNC: 7809

OMIM: 162010

KEGG: hsa:4804

STRING: 9606.ENSP00000172229

UniGene: Hs.415768

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