Name: NRG2 Antibody, FITC conjugated
Brand: CUSABIO
SKU: CSB-PA016078LC01HU

Product Details

Full Product Name	Rabbit anti-Homo sapiens (Human) NRG2 Polyclonal antibody
Uniprot No.	O14511
Target Names	NRG2
Alternative Names	Divergent of neuregulin 1 antibody; Divergent of neuregulin-1 antibody; Don 1 antibody; DON-1 antibody; Neural- and thymus-derived activator for ERBB kinases antibody; Neuregulin 2 antibody; Neuregulin-2 antibody; NRG-2 antibody; Nrg2 antibody; NRG2_HUMAN antibody; NTAK antibody; Pro NRG2 antibody; Pro-NRG2 antibody
Raised in	Rabbit
Species Reactivity	Human
Immunogen	Recombinant Human Pro-neuregulin-2, membrane-bound isoform protein (112-405AA)
Immunogen Species	Homo sapiens (Human)
Conjugate	FITC
Clonality	Polyclonal
Isotype	IgG
Purification Method	>95%, Protein G purified
Concentration	It differs from different batches. Please contact us to confirm it.
Buffer	Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form	Liquid
Troubleshooting and FAQs	Antibody FAQs
Storage	Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time	Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function	Direct ligand for ERBB3 and ERBB4 tyrosine kinase receptors. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. May also promote the heterodimerization with the EGF receptor.
Gene References into Functions	reduced expression of NRG2 led to marginal increase in cell survival under arsenite-induced stress. PMID: 27345716 examination of the effect of isoforms on angiogenesis PMID: 14722120 Nrg-2-induced Acetylcholine Receptor transcription requires an N-box motif and is regulated by alternative splicing. PMID: 15961242 Linkage interval for GLC1M was refined to a smaller region. The NRG2 gene was excluded as the causative gene for juvenile-onset primary open angle glaucoma. PMID: 17563728 Gln43 of NRG2beta is both necessary and sufficient for NRG2 stimulation of ErbB4 coupling to IL3 independence. PMID: 17945187 NRG2 was positive in almost all breast cancers studied. High expression is related to the biological aggressiveness of breast cancer. PMID: 17962208 Show More Hide All
Subcellular Location	[Pro-neuregulin-2, membrane-bound isoform]: Cell membrane; Single-pass type I membrane protein.; [Neuregulin-2]: Secreted.
Protein Families	Neuregulin family
Tissue Specificity	Restricted to the cerebellum in the adult.
Database Links	HGNC: 7998 OMIM: 603818 KEGG: hsa:9542 STRING: 9606.ENSP00000354910 UniGene: Hs.408515

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Code	CSB-PA016078LC01HU
Size	US$299
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NRG2 Antibody, FITC conjugated