PCGF6 Antibody

Datasheet
Code CSB-PA871612LA01HU
See More Details
Size US$299
Uniprot No. Q9BYE7
Image
  • Western Blot
    Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate
    All lanes: PCGF6 antibody at 3.1μg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 40, 31 kDa
    Observed band size: 40 kDa

Immunogen Recombinant Human Polycomb group RING finger protein 6 protein (9-70AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB; Recommended dilution: WB:1:500-1:5000
Relevance Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134), PCGF6, MBLR RNF134
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Research Area Epigenetics and Nuclear Signaling
Target Names PCGF6
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcriptional repressor
Subcellular Location Nucleus
Tissue Specificity Ubiquitous.
Database Links

HGNC: 21156

OMIM: 607816

KEGG: hsa:84108

STRING: 9606.ENSP00000358862

UniGene: Hs.335808

Pathway Signaling pathways regulating pluripotency of stem cells

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