PCGF6 Antibody

Code CSB-PA871612LA01HU
See More Details Free Antibody trial simple
Size US$299
Uniprot No. Q9BYE7
  • Western Blot
    Positive WB detected in: PC-3 whole cell lysate, MCF-7 whole cell lysate
    All lanes: PCGF6 antibody at 3.1μg/ml
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 40, 31 kDa
    Observed band size: 40 kDa

Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Recombinant Human Polycomb group RING finger protein 6 protein (9-70AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB; Recommended dilution: WB:1:500-1:5000
Relevance Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Purification Method >95%, Protein G purified
Isotype IgG
Clonality Polyclonal
Alias Polycomb group RING finger protein 6 (Mel18 and Bmi1-like RING finger) (RING finger protein 134), PCGF6, MBLR RNF134
Immunogen Species Human
Research Area Epigenetics and Nuclear Signaling
Target Names PCGF6
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Transcriptional repressor
Subcellular Location Nucleus
Tissue Specificity Ubiquitous.
Database Links

HGNC: 21156

OMIM: 607816

KEGG: hsa:84108

STRING: 9606.ENSP00000358862

UniGene: Hs.335808

Pathway Signaling pathways regulating pluripotency of stem cells

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