PDIA4 Antibody

Code CSB-PA017722GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PDIA4
Alternative Names
Calcium binding protein intestinal related antibody; Endoplasmic reticulum resident protein 70 antibody; Endoplasmic reticulum resident protein 72 antibody; EPR70 antibody; EPR72 antibody; ER protein 70 antibody; ER protein 72 antibody; ERP 70 antibody; ERp 72 antibody; ERp-72 antibody; ERp70 antibody; ERp72 antibody; PDIA 4 antibody; Pdia4 antibody; PDIA4_HUMAN antibody; PDIR antibody; Protein disulfide isomerase A4 antibody; Protein disulfide isomerase associated 4 antibody; Protein disulfide isomerase family A member 4 antibody; protein disulfide isomerase related protein (calcium-binding protein; intestinal-related) antibody; Protein disulfide isomerase related protein antibody; Protein disulfide-isomerase A4 antibody; Protein ERp 72 antibody; Protein ERp72 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PDIA4
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB,IHC,IF
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Gene References into Functions
  1. up-regulated by IL11 in first trimester placenta PMID: 28487027
  2. PDIA4 as a negative regulator of cancer cell apoptosis. PMID: 28534513
  3. Participants with metabolic syndrome (MetS) had significantly higher serum PDIA4 levels than those without MetS (P<0.001). After adjustments, the individuals with the highest PDIA4 tertile were associated with a higher risk of MetS than those with the lowest tertile (OR = 4.83, 95% CI: 2.71-8.60). PMID: 28650993
  4. CDDP-resistant non-small lung cancer cells undergo profound remodeling of their endoplasmic reticulum (ER) proteome (>80 proteins identified by proteomics) and exhibit a dramatic overexpression of two protein disulfide isomerases, PDIA4 and PDIA6. PMID: 24464223
  5. novel esophageal squamous cell carcinoma marker PDIA4 was identified by mass spectrometry and immunohistochemical analysis PMID: 21743296
  6. Nox1 associates with ERp72, which involves its N-terminus encompassing a Ca(2+)-binding site and the first TRX-like motif. PMID: 18620548

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Subcellular Location
Endoplasmic reticulum lumen. Melanosome.
Protein Families
Protein disulfide isomerase family
Database Links

HGNC: 30167

KEGG: hsa:9601

STRING: 9606.ENSP00000286091

UniGene: Hs.93659

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7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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