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PDIA4 Antibody, HRP conjugated

Datasheet
Code CSB-PA017722LB01HU
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDIA4 Polyclonal antibody
Uniprot No.
P13667
Target Names
PDIA4
Alternative Names
Calcium binding protein intestinal related antibody; Endoplasmic reticulum resident protein 70 antibody; Endoplasmic reticulum resident protein 72 antibody; EPR70 antibody; EPR72 antibody; ER protein 70 antibody; ER protein 72 antibody; ERP 70 antibody; ERp 72 antibody; ERp-72 antibody; ERp70 antibody; ERp72 antibody; PDIA 4 antibody; Pdia4 antibody; PDIA4_HUMAN antibody; PDIR antibody; Protein disulfide isomerase A4 antibody; Protein disulfide isomerase associated 4 antibody; Protein disulfide isomerase family A member 4 antibody; protein disulfide isomerase related protein (calcium-binding protein; intestinal-related) antibody; Protein disulfide isomerase related protein antibody; Protein disulfide-isomerase A4 antibody; Protein ERp 72 antibody; Protein ERp72 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Protein disulfide-isomerase A4 protein (101-400AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
HRP
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
ELISA Protocol
Troubleshooting and FAQs
Antibody FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Gene References into Functions
  1. up-regulated by IL11 in first trimester placenta PMID: 28487027
  2. PDIA4 as a negative regulator of cancer cell apoptosis. PMID: 28534513
  3. Participants with metabolic syndrome (MetS) had significantly higher serum PDIA4 levels than those without MetS (P<0.001). After adjustments, the individuals with the highest PDIA4 tertile were associated with a higher risk of MetS than those with the lowest tertile (OR = 4.83, 95% CI: 2.71-8.60). PMID: 28650993
  4. CDDP-resistant non-small lung cancer cells undergo profound remodeling of their endoplasmic reticulum (ER) proteome (>80 proteins identified by proteomics) and exhibit a dramatic overexpression of two protein disulfide isomerases, PDIA4 and PDIA6. PMID: 24464223
  5. novel esophageal squamous cell carcinoma marker PDIA4 was identified by mass spectrometry and immunohistochemical analysis PMID: 21743296
  6. Nox1 associates with ERp72, which involves its N-terminus encompassing a Ca(2+)-binding site and the first TRX-like motif. PMID: 18620548

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Subcellular Location
Endoplasmic reticulum lumen. Melanosome.
Protein Families
Protein disulfide isomerase family
Database Links

HGNC: 30167

KEGG: hsa:9601

STRING: 9606.ENSP00000286091

UniGene: Hs.93659

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Related pathways
Protein processing in endoplasmic reticulum Th17 cell differentiation Thyroid hormone synthesis
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