PDLIM3 Antibody

Code CSB-PA017734GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
Alternative Names
Actinin associated LIM protein antibody; Actinin-associated LIM protein antibody; Alpha actinin 2 associated LIM protein antibody; Alpha-actinin-2-associated LIM protein antibody; DKFZp686L0362 antibody; Enigma homolog antibody; PDLI3_HUMAN antibody; PDLIM 3 antibody; PDLIM3 antibody; PDZ and LIM domain 3 antibody; PDZ and LIM domain protein 3 antibody
Raised in
Species Reactivity
Human PDLIM3
Immunogen Species
Homo sapiens (Human)
Purification Method
Antigen Affinity Purified
It differs from different batches. Please contact us to confirm it.
PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
Troubleshooting and FAQs
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

May play a role in the organization of actin filament arrays within muscle cells.
Gene References into Functions
  1. This study confirmed that PDLIM3 as genetic modifiers of age at onset of Alzheimer disease. PMID: 26214276
  2. two abnormal splicing events for actinin-associated LIM protein 3 (PDLIM3/ALP) and fibronectin 1 (FN1) in the skeletal muscles of myotonic dystrophy type 1 patients. PMID: 21549096
  3. mutations in PDLIM3 and MYPN are infrequent in hypertrophic cardiomyopathies PMID: 20801532
  4. ZASP-like motif in actinin-associated LIM protein is required for interaction with the alpha-actinin rod and for targeting to the muscle Z-line PMID: 15084604
  5. Mutations in PDLIM3 and MYOZ1, encoding myocyte Z line proteins, do not play any significant role in the genetic etiology of idiopathic DCM. PMID: 17254821

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Subcellular Location
Cytoplasm, myofibril, sarcomere, Z line. Note=Localizes to myofiber Z-lines.
Tissue Specificity
Isoform 1 is highly expressed in differentiated skeletal muscle. Isoform 2 is heart-specific.
Database Links

HGNC: 20767

OMIM: 605889

KEGG: hsa:27295

STRING: 9606.ENSP00000284770

UniGene: Hs.701364

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