PDZD3 Antibody

Datasheet

Code	CSB-PA017753GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

Q86UT5

Target Names

PDZD3

Alternative Names

IKEPP antibody; Intestinal and kidney enriched PDZ protein antibody; Intestinal and kidney-enriched PDZ protein antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF4 antibody; Na/Pi cotransporter C terminal associated protein 2 antibody; Na/Pi cotransporter C-terminal-associated protein 2 antibody; NaPi-Cap2 antibody; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 antibody; NHERF-4 antibody; NHERF4 antibody; NHRF4_HUMAN antibody; PDZ domain containing 2 antibody; PDZ domain containing 3 antibody; PDZ domain containing protein 2 antibody; PDZ domain-containing protein 2 antibody; PDZ domain-containing protein 3 antibody; PDZD 3 antibody; Pdzd3 antibody; PDZK2 antibody; Protein DLNB27 antibody; Sodium-hydrogen exchanger regulatory factor 4 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PDZD3

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.

Gene References into Functions

The NHERF4 is a novel modulator of luminal fluidity in the intestine by adjusting SLC26A3 expression and activity through a phosphorylation-dependent mechanism. PMID: 22627094
IKEPP was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP PMID: 22884631
A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor. PMID: 11950846
Regulation of NHE3 depends on the nature of the NHERF family member associating with NHE3 and the accompanying NHE3 complexes. PMID: 19088451

Subcellular Location

Cell membrane; Peripheral membrane protein. Cytoplasm.

Tissue Specificity

Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin.

Database Links

HGNC: 19891

OMIM: 607146

KEGG: hsa:79849

STRING: 9606.ENSP00000347742

UniGene: Hs.374726

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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