PDZD3 Antibody

Code CSB-PA774807LA01HU
Size US$166
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  • Western blot
    All lanes: PDZD3 antibody at 2µg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse heart tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 62, 55, 53, 42, 25 kDa
    Observed band size: 62 kDa

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA774807LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDZD3 Polyclonal antibody
Uniprot No.
Target Names
PDZD3
Alternative Names
IKEPP antibody; Intestinal and kidney enriched PDZ protein antibody; Intestinal and kidney-enriched PDZ protein antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF4 antibody; Na/Pi cotransporter C terminal associated protein 2 antibody; Na/Pi cotransporter C-terminal-associated protein 2 antibody; NaPi-Cap2 antibody; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 antibody; NHERF-4 antibody; NHERF4 antibody; NHRF4_HUMAN antibody; PDZ domain containing 2 antibody; PDZ domain containing 3 antibody; PDZ domain containing protein 2 antibody; PDZ domain-containing protein 2 antibody; PDZ domain-containing protein 3 antibody; PDZD 3 antibody; Pdzd3 antibody; PDZK2 antibody; Protein DLNB27 antibody; Sodium-hydrogen exchanger regulatory factor 4 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF4 protein (42-291AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PDZD3 Antibody (Product code: CSB-PA774807LA01HU) is Non-conjugated. For PDZD3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA774807LB01HU PDZD3 Antibody, HRP conjugated ELISA
FITC CSB-PA774807LC01HU PDZD3 Antibody, FITC conjugated
Biotin CSB-PA774807LD01HU PDZD3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Gene References into Functions
  1. The NHERF4 is a novel modulator of luminal fluidity in the intestine by adjusting SLC26A3 expression and activity through a phosphorylation-dependent mechanism. PMID: 22627094
  2. IKEPP was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP PMID: 22884631
  3. A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor. PMID: 11950846
  4. Regulation of NHE3 depends on the nature of the NHERF family member associating with NHE3 and the accompanying NHE3 complexes. PMID: 19088451
Subcellular Location
Cell membrane; Peripheral membrane protein. Cytoplasm.
Tissue Specificity
Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin.
Database Links

HGNC: 19891

OMIM: 607146

KEGG: hsa:79849

STRING: 9606.ENSP00000347742

UniGene: Hs.374726

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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