PDZD3 Antibody

Code CSB-PA774807LA01HU
Size US$166
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  • Western blot
    All lanes: PDZD3 antibody at 2µg/ml
    Lane 1: Mouse kidney tissue
    Lane 2: Mouse heart tissue
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 62, 55, 53, 42, 25 kDa
    Observed band size: 62 kDa

  • Immunohistochemistry of paraffin-embedded human skin tissue using CSB-PA774807LA01HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PDZD3 Polyclonal antibody
Uniprot No.
Target Names
PDZD3
Alternative Names
IKEPP antibody; Intestinal and kidney enriched PDZ protein antibody; Intestinal and kidney-enriched PDZ protein antibody; Na(+)/H(+) exchange regulatory cofactor NHE-RF4 antibody; Na/Pi cotransporter C terminal associated protein 2 antibody; Na/Pi cotransporter C-terminal-associated protein 2 antibody; NaPi-Cap2 antibody; Natrium-phosphate cotransporter IIa C-terminal-associated protein 2 antibody; NHERF-4 antibody; NHERF4 antibody; NHRF4_HUMAN antibody; PDZ domain containing 2 antibody; PDZ domain containing 3 antibody; PDZ domain containing protein 2 antibody; PDZ domain-containing protein 2 antibody; PDZ domain-containing protein 3 antibody; PDZD 3 antibody; Pdzd3 antibody; PDZK2 antibody; Protein DLNB27 antibody; Sodium-hydrogen exchanger regulatory factor 4 antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Na(+)/H(+) exchange regulatory cofactor NHE-RF4 protein (42-291AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PDZD3 Antibody (Product code: CSB-PA774807LA01HU) is Non-conjugated. For PDZD3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA774807LB01HU PDZD3 Antibody, HRP conjugated ELISA
FITC CSB-PA774807LC01HU PDZD3 Antibody, FITC conjugated
Biotin CSB-PA774807LD01HU PDZD3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Acts as a regulatory protein that associates with GUCY2C and negatively modulates its heat-stable enterotoxin-mediated activation. Stimulates SLC9A3 activity in the presence of elevated calcium ions.
Gene References into Functions
  1. The NHERF4 is a novel modulator of luminal fluidity in the intestine by adjusting SLC26A3 expression and activity through a phosphorylation-dependent mechanism. PMID: 22627094
  2. IKEPP was also found to be expressed in vascular endothelial cells where it co-localizes and complexes with the hIP PMID: 22884631
  3. A novel PDZ protein regulates the activity of guanylyl cyclase C, the heat-stable enterotoxin receptor. PMID: 11950846
  4. Regulation of NHE3 depends on the nature of the NHERF family member associating with NHE3 and the accompanying NHE3 complexes. PMID: 19088451
Subcellular Location
Cell membrane; Peripheral membrane protein. Cytoplasm.
Tissue Specificity
Expressed in kidney and the gastrointestinal tract. Not detected in brain, heart, skeletal muscle or cells of hematopoietic origin.
Database Links

HGNC: 19891

OMIM: 607146

KEGG: hsa:79849

STRING: 9606.ENSP00000347742

UniGene: Hs.374726

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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