PGA3 Antibody

Code CSB-PA11289A0Rb
Size US$166
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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PGA3 Polyclonal antibody
Uniprot No.
Target Names
PGA3
Alternative Names
PGA3 antibody; Pepsin A-3 antibody; EC 3.4.23.1 antibody; Pepsinogen-3 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Pepsin A-3 protein (16-388AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PGA3 Antibody (Product code: CSB-PA11289A0Rb) is Non-conjugated. For PGA3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA11289B0Rb PGA3 Antibody, HRP conjugated ELISA
FITC CSB-PA11289C0Rb PGA3 Antibody, FITC conjugated
Biotin CSB-PA11289D0Rb PGA3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function
Shows particularly broad specificity; although bonds involving phenylalanine and leucine are preferred, many others are also cleaved to some extent.
Gene References into Functions
  1. Low Pepsinogen I is associated with precancerous gastric lesions. PMID: 25292040
  2. High serum Pepsinogen I level is associ9ated with the progression of gastric precancerous lesions. PMID: 24895149
  3. Significantly higher AUC was observed for the PGI/PGII ratio and is associated with atrophy and intestinal metaplasia. PMID: 23886209
  4. A significant negative correlation was found between the degree of corpus atrophy and the level of serum pepsinogen-I in atrophic gastritis patients with gastroesophageal reflux. PMID: 21175799
  5. Higher levels of Pepsinogen I is associated with early gastric cancer PMID: 15688378
  6. Helicobacter pylori eradication improves gastric histology and decreases serum gastrin, pepsinogen I and pepsinogen II levels in patients with duodenal ulcer. PMID: 17559360
  7. pepsinogens may have a role in esophageal squamous dysplasia PMID: 18844222
  8. Barrett's esophagus is characterized by the absence of Helicobacter pylori infection and high levels of serum pepsinogen I concentration in Japan. PMID: 19196398

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Subcellular Location
Secreted.
Protein Families
Peptidase A1 family
Database Links

HGNC: 8885

OMIM: 169700

KEGG: hsa:643834

STRING: 9606.ENSP00000322192

UniGene: Hs.601055

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