PGLYRP3 Antibody

Code CSB-PA017864LA01HU
Size US$166
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  • Western Blot
    Positive WB detected in: MCF-7 whole cell lysate, Colo320 whole cell lysate
    All lanes: PGLYRP3 antibody at 4.86µg/ml
    Secondary
    Goat polyclonal to rabbit IgG at 1/50000 dilution
    Predicted band size: 38 kDa
    Observed band size: 38 kDa

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PGLYRP3 Polyclonal antibody
Uniprot No.
Target Names
PGLYRP3
Alternative Names
PGLYRP3 antibody; PGRPIA antibody; Peptidoglycan recognition protein 3 antibody; Peptidoglycan recognition protein I-alpha antibody; PGLYRPIalpha antibody; PGRP-I-alpha antibody; Peptidoglycan recognition protein intermediate alpha antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Peptidoglycan recognition protein 3 protein (90-222AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated

The PGLYRP3 Antibody (Product code: CSB-PA017864LA01HU) is Non-conjugated. For PGLYRP3 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA017864LB01HU PGLYRP3 Antibody, HRP conjugated ELISA
FITC CSB-PA017864LC01HU PGLYRP3 Antibody, FITC conjugated
Biotin CSB-PA017864LD01HU PGLYRP3 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
Gene References into Functions
  1. anti-inflammatory role in intestinal epithelial cells during antibacterial immune response PMID: 22099350
  2. expression of PGlyRP3 can be regulated by dietary factors such as probiotic oligosaccharides; PPARgamma is involved in regulation of expression of PGlyRP3 in intestinal mucosa by dietary components PMID: 21451128
  3. Data are consistent with previous reports of association of psoriasis with genes on 1q21, and suggest a role for Pglyrp3 in skin biology. PMID: 16362825
Subcellular Location
Secreted.
Protein Families
N-acetylmuramoyl-L-alanine amidase 2 family
Tissue Specificity
Detected in skin epidermis, eccrine sweat glands and ducts, ciliary body epithelial cells of the eye, in small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). Highly expressed in skin and esophagus, expressed als
Database Links

HGNC: 30014

OMIM: 608197

KEGG: hsa:114771

STRING: 9606.ENSP00000290722

UniGene: Hs.348266

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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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