PHKG2 Antibody

Datasheet

Code	CSB-PA941646
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA941646(PHKG2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA941646(PHKG2 Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200) Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A549 cells, Hela cells, HepG2 cells, 293T cells, Primary antibody: CSB-PA941646(PHKG2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P15735

Target Names

PHKG2

Alternative Names

PHKG2Phosphorylase b kinase gamma catalytic chain antibody; liver/testis isoform antibody; PHK-gamma-LT antibody; PHK-gamma-T antibody; EC 2.7.11.19 antibody; PSK-C3 antibody; Phosphorylase kinase subunit gamma-2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide of Human PHKG2

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:1000-1:2000
WB	1:200-1:1000
IHC	1:25-1:100

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Catalytic subunit of the phosphorylase b kinase (PHK), which mediates the neural and hormonal regulation of glycogen breakdown (glycogenolysis) by phosphorylating and thereby activating glycogen phosphorylase. May regulate glycogeneolysis in the testis. In vitro, phosphorylates PYGM.

Gene References into Functions

These cases add to the current knowledge of clinical variability in patients with PHKG2 mutations. Long term studies, involving follow-up of these patients into adulthood, are needed PMID: 24389071
Patients with PHKG2 mutations have a severe hepatic phenotype within the heterogeneous GSD IX disorder. A defect in PHKG2 should be considered in patients with suspected glycogenosis associated with significant liver fibrosis and cirrhosis. PMID: 24326380
PHKG2 mutations are associated with Glycogen storage disease type IX PMID: 17689125

Involvement in disease

Glycogen storage disease 9C (GSD9C)

Protein Families

Protein kinase superfamily, CAMK Ser/Thr protein kinase family

Database Links

HGNC: 8931

OMIM: 172471

KEGG: hsa:5261

STRING: 9606.ENSP00000455607

UniGene: Hs.65735

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Calcium signaling pathway Glucagon signaling pathway Insulin signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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