PMPCA Antibody

Datasheet

Code	CSB-PA606021ESR1HU
Size	US$166
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Image	Immunohistochemistry of paraffin-embedded human colon cancer using CSB-PA606021ESR1HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human endometrial cancer using CSB-PA606021ESR1HU at dilution of 1:100
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PMPCA Polyclonal antibody

Uniprot No.

Q10713

Target Names

PMPCA

Alternative Names

1200002L24Rik antibody; 4933435E07Rik antibody; Alpha MPP antibody; Alpha-MPP antibody; FLJ26258 antibody; Inositol polyphosphate 5 phosphatase, 72 kD antibody; INPP5E antibody; KIAA0123 antibody; MGC104197 antibody; MGC93916 antibody; Mitochondrial matrix processing protease, alpha subunit antibody; mitochondrial processing peptidase subunit alpha antibody; Mitochondrial-processing peptidase subunit alpha antibody; MPPA_HUMAN antibody; P 55 antibody; P-55 antibody; Peptidase (mitochondrial processing) alpha antibody; pmpca antibody; RP11-413M3.1 antibody; RP23-306D20.8 antibody; SCAR2 antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Mitochondrial-processing peptidase subunit alpha protein (456-525AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form

Liquid

Tested Applications

ELISA, IHC

Recommended Dilution

Application	Recommended Dilution
IHC	1:20-1:200

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

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Target Background

Function

Substrate recognition and binding subunit of the essential mitochondrial processing protease (MPP), which cleaves the mitochondrial sequence off newly imported precursors proteins.

Gene References into Functions

study represents the first time that defects in PMPCA and mitochondrial processing peptidase have been described in association with a disease phenotype in humans. PMID: 25808372
OxLDL triggers retrograde translocation of arginase2 in aortic endothelial cells via ROCK and mitochondrial processing peptidase. PMID: 24903103

Involvement in disease

Spinocerebellar ataxia, autosomal recessive, 2 (SCAR2)

Subcellular Location

Mitochondrion matrix. Mitochondrion inner membrane.

Protein Families

Peptidase M16 family

Tissue Specificity

Ubiquitously expressed with highest expression in fetal tissues and adult brain, cerebellum and cerebellar vermis.

Database Links

HGNC: 18667

OMIM: 213200

KEGG: hsa:23203

STRING: 9606.ENSP00000360782

UniGene: Hs.495471

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Virus Infection Target Therapy

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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