PPM1H Antibody

Datasheet

Citations (1)

Code	CSB-PA892345LA01HU
Size	US$166
	Order now
Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA892345LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human liver tissue using CSB-PA892345LA01HU at dilution of 1:100 Immunofluorescent analysis of MCF-7 cells using CSB-PA892345LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Western Blot Positive WB detected in: Mouse stomach tissue, Mouse kidney tissue, Mouse skeletal muscle tissue All lanes: PPM1H antibody at 3.2μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 57 kDa Observed band size: 57 kDa
Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Citations
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PPM1H Polyclonal antibody

Uniprot No.

Q9ULR3

Target Names

PPM1H

Alternative Names

PPM1H antibody; ARHCL1 antibody; KIAA1157 antibody; URCC2 antibody; Protein phosphatase 1H antibody; EC 3.1.3.16 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Recombinant Human Protein phosphatase 1H protein (73-289AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PPM1H Antibody (Product code: CSB-PA892345LA01HU) is Non-conjugated. For PPM1H Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA892345LB01HU	PPM1H Antibody, HRP conjugated	ELISA
FITC	CSB-PA892345LC01HU	PPM1H Antibody, FITC conjugated
Biotin	CSB-PA892345LD01HU	PPM1H Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:2000-1:10000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

PPM1H is Down-Regulated by ATF6 and Dephosphorylates p-RPS6KB1 to Inhibit Progression of Hepatocellular Carcinoma X Yang,Research Square,2021

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

Submit a Review here

Applications : Western blot analysis

Sample type: Human cells

Review: Western blot analysis of the indicated protein level in PPM1H-overexpressed HepG2 cells with or without insulin treatment.

By Anonymous

Target Background

Function

Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.

Gene References into Functions

PPM1H may be a new tumor-suppressor factor for pancreatic cancer and provides new insight into molecular targets for gene therapy of pancreatic cancer PMID: 27599670
PPM1H acts as a gatekeeper to prevent excessive BMP signaling through dephosphorylation and subsequent nuclear exclusion of P-Smad1/5/8 proteins. PMID: 24732009
Knockdown of the serine/threonine phosphatase PPM1H confers trastuzumab resistance via reduction in protein levels of the tumor suppressor p27. PMID: 22586611
PPM1H, overexpressed in colon adenocarcinoma, is associated with CSE1L protein. PMID: 18059182

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

PP2C family

Database Links

HGNC: 18583

OMIM: 616016

KEGG: hsa:57460

UniGene: Hs.435479

Promotions

CUSABIO Premium Active Proteins 20% OFF SALE

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
Please enter the characters shown. Click the image to refresh if unclear.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address