PPM1H Antibody

Datasheet

Citations (1)

Code	CSB-PA892345LA01HU
Size	US$166
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Image	Western Blot Positive WB detected in: SK-BR-3 whole cell lysate(30µg), HT29 whole cell lysate(30µg), K562 whole cell lysate(30µg), HPAC whole cell lysate(30µg), HepG2 whole cell lysate(30µg),)Mouse brain tissue whole cell lysate(30µg) All lanes: PPM1H antibody at 1:1000 Secondary Goat polyclonal to rabbit IgG at 1/40000 dilution Predicted band size: 56 kDa Observed band size: 56 kDa Exposure time: 120s
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Product Details
Citations
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PPM1H Polyclonal antibody

Uniprot No.

Q9ULR3

Target Names

PPM1H

Alternative Names

PPM1H antibody; ARHCL1 antibody; KIAA1157 antibody; URCC2 antibody; Protein phosphatase 1H antibody; EC 3.1.3.16 antibody

Raised in

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide of human PPM1H

Immunogen Species

Homo sapiens (Human)

Clonality

Polyclonal

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Form

Liquid

Tested Applications

ELISA, WB

Recommended Dilution

Application	Recommended Dilution
WB	1:500-1:2000

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Citations

PPM1H is Down-Regulated by ATF6 and Dephosphorylates p-RPS6KB1 to Inhibit Progression of Hepatocellular Carcinoma X Yang,Research Square,2021

Customer Reviews and Q&A

■ Customer Reviews

Average Rating:

5.0 - 1 reviews

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Applications : Western blot analysis

Sample type: Human cells

Review: Western blot analysis of the indicated protein level in PPM1H-overexpressed HepG2 cells with or without insulin treatment.

By Anonymous

Target Background

Function

Dephosphorylates CDKN1B at 'Thr-187', thus removing a signal for proteasomal degradation.

Gene References into Functions

PPM1H may be a new tumor-suppressor factor for pancreatic cancer and provides new insight into molecular targets for gene therapy of pancreatic cancer PMID: 27599670
PPM1H acts as a gatekeeper to prevent excessive BMP signaling through dephosphorylation and subsequent nuclear exclusion of P-Smad1/5/8 proteins. PMID: 24732009
Knockdown of the serine/threonine phosphatase PPM1H confers trastuzumab resistance via reduction in protein levels of the tumor suppressor p27. PMID: 22586611
PPM1H, overexpressed in colon adenocarcinoma, is associated with CSE1L protein. PMID: 18059182

Subcellular Location

Nucleus. Cytoplasm.

Protein Families

PP2C family

Database Links

HGNC: 18583

OMIM: 616016

KEGG: hsa:57460

UniGene: Hs.435479

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Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

No. 269, Shendun 5th Road, Donghu Hi-Tech Development Area, Hubei Province, 430206, P.R.China

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