PPP1R12B Antibody

Datasheet

Code	CSB-PA018512GA01HU
Size	$600
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Product Details
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Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

O60237

Target Names

PPP1R12B

Alternative Names

PPP1R12B antibody; MYPT2 antibody; Protein phosphatase 1 regulatory subunit 12B antibody; Myosin phosphatase-targeting subunit 2 antibody; Myosin phosphatase target subunit 2 antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Human PPP1R12B

Immunogen Species

Homo sapiens (Human)

Isotype

IgG

Purification Method

Antigen Affinity Purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.

Tested Applications

ELISA,WB

Protocols

ELISA Protocol
Western Blotting(WB) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus.

Gene References into Functions

PPP1R12B is associated with childhood asthma in a Russian population. PMID: 23640410
Results describe the characterization and function of MYPT2, a target subunit of myosin phosphatase in heart. PMID: 16431080
analysis of the interaction between the coiled coil leucine zipper of cGMP-dependent protein kinase Ialpha and the C terminus of the myosin binding subunit of the myosin light chain phosphatase PMID: 18782776

Subcellular Location

Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, stress fiber.

Tissue Specificity

Detected in skeletal muscle, fetal and adult heart, brain, placenta, kidney, spleen, thymus, pancreas and lung. Isoform 3 and isoform 4 are heart specific.

Database Links

HGNC: 7619

OMIM: 603768

KEGG: hsa:4660

STRING: 9606.ENSP00000384496

UniGene: Hs.444403

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Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Focal adhesion Regulation of actin cytoskeleton Vascular smooth muscle contraction

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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