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| Code | CSB-PA727750LD01HU |
| Size | US$299 How to order? |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Homo sapiens (Human) PPP2R2D Polyclonal antibody |
| Uniprot No. | Q66LE6 |
| Target Names | PPP2R2D |
| Alternative Names | 2ABD_HUMAN antibody; MDS026 antibody; PP2A subunit B isoform B55-delta antibody; PP2A subunit B isoform delta antibody; PP2A subunit B isoform PR55-delta antibody; PP2A subunit B isoform R2-delta antibody; PPP2R2D antibody; Protein phosphatase 2 regulatory subunit B delta antibody; Protein phosphatase 2 regulatory subunit B delta isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform antibody |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Immunogen | Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein (1-192AA) |
| Immunogen Species | Homo sapiens (Human) |
| Conjugate | Biotin |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | >95%, Protein G purified |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Form | Liquid |
| Tested Applications | ELISA |
| Protocols | ELISA Protocol |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function |
B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.
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| Gene References into Functions |
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| Subcellular Location | Cytoplasm. |
| Protein Families | Phosphatase 2A regulatory subunit B family |
| Database Links |
HGNC: 23732 OMIM: 613992 KEGG: hsa:55844 STRING: 9606.ENSP00000399970 UniGene: Hs.380372 |
