PPP2R2D Antibody

Datasheet

Code	CSB-PA727750LA01HU
Size	US$166
	Order now
Image	Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA727750LA01HU at dilution of 1:100 Immunohistochemistry of paraffin-embedded human glioma using CSB-PA727750LA01HU at dilution of 1:100 Immunofluorescent analysis of Hela cells using CSB-PA727750LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L) Western Blot Positive WB detected in: U87 whole cell lysate, PC-3 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate All lanes: PPP2R2D antibody at 3.3μg/ml Secondary Goat polyclonal to rabbit IgG at 1/50000 dilution Predicted band size: 53 kDa Observed band size: 53 kDa
Promotion
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Full Product Name

Rabbit anti-Homo sapiens (Human) PPP2R2D Polyclonal antibody

Uniprot No.

Q66LE6

Target Names

PPP2R2D

Alternative Names

2ABD_HUMAN antibody; MDS026 antibody; PP2A subunit B isoform B55-delta antibody; PP2A subunit B isoform delta antibody; PP2A subunit B isoform PR55-delta antibody; PP2A subunit B isoform R2-delta antibody; PPP2R2D antibody; Protein phosphatase 2 regulatory subunit B delta antibody; Protein phosphatase 2 regulatory subunit B delta isoform antibody; Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Recombinant Human Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B delta isoform protein (1-192AA)

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

The PPP2R2D Antibody (Product code: CSB-PA727750LA01HU) is Non-conjugated. For PPP2R2D Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA727750LB01HU	PPP2R2D Antibody, HRP conjugated	ELISA
FITC	CSB-PA727750LC01HU	PPP2R2D Antibody, FITC conjugated
Biotin	CSB-PA727750LD01HU	PPP2R2D Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA, WB, IHC, IF

Recommended Dilution

Application	Recommended Dilution
WB	1:1000-1:5000
IHC	1:20-1:200
IF	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Usage

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.

Gene References into Functions

Results show that PPP2R2D expression was significantly upregulated at the mRNA and protein levels in gastric cancer (GC) tissues and correlated with poor prognosis. Further evidence demonstrates an oncogenic role of PPP2R2D in GC progression and development through regulation of mTOR. PMID: 29568966
The PP2A regulatory subunit PPP2R2D inhibits T-cell proliferation and survival within tumors. PMID: 24596207
The -462 G>A variant of PPP2R2D affects NF1 binding to the proximal promoter of PPP2R2D. PMID: 22539979
These highly related members of the same subfamily of PP2A regulatory subunits differentially regulate TGF-beta/Activin/Nodal signalling to elicit opposing biological outcomes. PMID: 18697906

Subcellular Location

Cytoplasm.

Protein Families

Phosphatase 2A regulatory subunit B family

Database Links

HGNC: 23732

OMIM: 613992

KEGG: hsa:55844

STRING: 9606.ENSP00000399970

UniGene: Hs.380372

Promotions

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Hippo signaling pathway PI3K-Akt signaling pathway AMPK signaling Sphingolipid signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：
If CAPTCHA verification fails, click to refresh the CAPTCHA and try again.

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address