PPP2R3C Antibody

Code CSB-PA836171ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: PPP2R3C antibody at 3.76µg/ml
    Lane 1: Mouse stomach tissue
    Lane 2: A431 whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Lane 4: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 54, 40 kDa
    Observed band size: 54 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA836171ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA836171ESR2HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PPP2R3C Polyclonal antibody
Uniprot No. Q969Q6
Target Names PPP2R3C
Alternative Names C14orf10 antibody; Chromosome 14 open reading frame 10 antibody; G4-1 antibody; G5pr antibody; Hypothetical protein FLJ20644 antibody; P2R3C_HUMAN antibody; ppp2r3c antibody; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma antibody; Protein phosphatase 2 regulatory subunit B''gamma antibody; protein phosphatase 2, regulatory subunit B'', gamma antibody; Protein phosphatase subunit G5PR antibody; rhabdomyosarcoma antigen MU-RMS-40.6A antibody; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C antibody; rhabdomyosarcoma antigen Mu-RMS-40.6C antibody; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma antibody
Raised in Rabbit
Species Reactivity Human, Mouse
Immunogen Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B\\\'\\\' subunit gamma protein (1-160AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
Gene References into Functions
  1. Knockdown of PP5 and/or PPP2R3C increased P-gp expression and lowered the sensitivity to vincristine and doxorubicin. Consequently, results indicate that PP5/PPP2R3C negatively regulates P-gp expression and function. PMID: 24333728
  2. G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen. PMID: 22753944
Subcellular Location Nucleus, Cytoplasm
Tissue Specificity Ubiquitously expressed in brain and other tissues.
Database Links

HGNC: 17485

OMIM: 615902

KEGG: hsa:55012

STRING: 9606.ENSP00000261475

UniGene: Hs.530712

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