PPP2R3C Antibody

Code CSB-PA836171ESR2HU
Size US$166
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  • Western blot
    All lanes: PPP2R3C antibody at 3.76µg/ml
    Lane 1: Mouse stomach tissue
    Lane 2: A431 whole cell lysate
    Lane 3: Jurkat whole cell lysate
    Lane 4: A549 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 54, 40 kDa
    Observed band size: 54 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA836171ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA836171ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) PPP2R3C Polyclonal antibody
Uniprot No.
Target Names
Alternative Names
C14orf10 antibody; Chromosome 14 open reading frame 10 antibody; G4-1 antibody; G5pr antibody; Hypothetical protein FLJ20644 antibody; P2R3C_HUMAN antibody; ppp2r3c antibody; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma antibody; Protein phosphatase 2 regulatory subunit B''gamma antibody; protein phosphatase 2, regulatory subunit B'', gamma antibody; Protein phosphatase subunit G5PR antibody; rhabdomyosarcoma antigen MU-RMS-40.6A antibody; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C antibody; rhabdomyosarcoma antigen Mu-RMS-40.6C antibody; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma antibody
Raised in
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B\\\'\\\' subunit gamma protein (1-160AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Usage
For Research Use Only. Not for use in diagnostic or therapeutic procedures.

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Target Background

Function
May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
Gene References into Functions
  1. Knockdown of PP5 and/or PPP2R3C increased P-gp expression and lowered the sensitivity to vincristine and doxorubicin. Consequently, results indicate that PP5/PPP2R3C negatively regulates P-gp expression and function. PMID: 24333728
  2. G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen. PMID: 22753944
Subcellular Location
Nucleus. Cytoplasm.
Tissue Specificity
Ubiquitously expressed in brain and other tissues.
Database Links

HGNC: 17485

OMIM: 615902

KEGG: hsa:55012

STRING: 9606.ENSP00000261475

UniGene: Hs.530712

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