PPP2R3C Antibody

Code CSB-PA003843
Size US$167 How to order?
  • Western Blot analysis of HuvEc cells using PPP2R3C Polyclonal Antibody
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Product Details

Uniprot No. Q969Q6
Target Names PPP2R3C
Alternative Names C14orf10 antibody; Chromosome 14 open reading frame 10 antibody; G4-1 antibody; G5pr antibody; Hypothetical protein FLJ20644 antibody; P2R3C_HUMAN antibody; ppp2r3c antibody; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma antibody; Protein phosphatase 2 regulatory subunit B''gamma antibody; protein phosphatase 2, regulatory subunit B'', gamma antibody; Protein phosphatase subunit G5PR antibody; rhabdomyosarcoma antigen MU-RMS-40.6A antibody; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C antibody; rhabdomyosarcoma antigen Mu-RMS-40.6C antibody; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma antibody
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Immunogen Synthesized peptide derived from the Internal region of Human PPP2R3C.
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Isotype IgG
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Form Liquid
Tested Applications WB, ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-1:2000
ELISA 1:20000
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
Gene References into Functions
  1. Knockdown of PP5 and/or PPP2R3C increased P-gp expression and lowered the sensitivity to vincristine and doxorubicin. Consequently, results indicate that PP5/PPP2R3C negatively regulates P-gp expression and function. PMID: 24333728
  2. G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen. PMID: 22753944
Subcellular Location Nucleus. Cytoplasm.
Tissue Specificity Ubiquitously expressed in brain and other tissues.
Database Links

HGNC: 17485

OMIM: 615902

KEGG: hsa:55012

STRING: 9606.ENSP00000261475

UniGene: Hs.530712

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7505 Fannin St. Ste 610-312, Houston, TX 77054, USA
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