PRMT3 Antibody

Code CSB-PA018733LA01HU
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
  • Western blot
    All lanes: PRMT3 antibody at 7μg/ml + MCF-7 whole cell lysate
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 60, 53 kDa
    Observed band size: 53 kDa

  • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA018733LA01HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human glioma using CSB-PA018733LA01HU at dilution of 1:100

  • Immunofluorescent analysis of MCF-7 cells using CSB-PA018733LA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PRMT3 Polyclonal antibody
Uniprot No. O60678
Target Names PRMT3
Alternative Names 2010005E20Rik antibody; 2410018A17Rik antibody; AL033309 antibody; ANM3_HUMAN antibody; Heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 3 antibody; Heterogeneous nuclear ribonucleoprotein methyltransferase like 3 antibody; Heterogeneous nuclear ribonucleoprotein methyltransferase like protein 3 antibody; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3 antibody; HMT1 hnRNP methyltransferase like 3 antibody; HMT1 hnRNP methyltransferase like 3 S. cerevisiae antibody; HMT1-like 3 antibody; hnRNP methyltransferase like 3 antibody; HRMT1L3 antibody; PRMT 3 antibody; PRMT3 antibody; Protein arginine methyltransferase 3 antibody; Protein arginine N methyltransferase 3 antibody; Protein arginine N-methyltransferase 3 antibody
Raised in Rabbit
Species Reactivity Human
Immunogen Recombinant Human Protein arginine N-methyltransferase 3 protein (311-529AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method >95%, Protein G purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form Liquid
Tested Applications ELISA, WB, IHC, IF
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
IHC 1:20-1:200
IF 1:50-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunofluorescence (IF) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.


Association Analysis of Single-Cell RNA Sequencing and Proteomics Reveals a Vital Role of Ca2+ Signaling in the Determination of Skeletal Muscle Development Potential.. K Qiu,Cells,2020

Applications: Western Blot
Sample type: Muscle Myo-lineage cells
Review: In order to verify the reliability of proteomics data, 7 DEPs were randomly selected for Western blot analysis. As shownin FigureS1, there lativea bundance sof selected proteins between Myo-L and Myo-Y determined by Western blot were highly consistent with the data of TMT analysis.
PMID: 32331484

Target Data

Function Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins.
Gene References into Functions
  1. Findings uncover the existence of an extra-ribosomal complex consisting of PDCD2L, RPS2, and PRMT3 and support a role for PDCD2L in the late maturation of 40S ribosomal subunits. PMID: 27697862
  2. This work profilies substrates of protein arginine N-methyltransferase 3 with S-adenosyl-L-methionine analogues. PMID: 24320160
  3. Mutational defects in PRMT3 is not the cause of frontotemporal lobar degeneration. PMID: 23635657
  4. results show that protein arginine methyl transferase (PRMT)-3 and -5 methylate NaV1.5 in vitro, interact with NaV1.5 in human embryonic kidney (HEK) cells, and increase NaV1.5 current density PMID: 23912080
  5. The crystal structure of PRMT3 in complex with an inhibitor as well as kinetic analysis reveals an allosteric site of inhibition. PMID: 22795084
  6. release of VHL30 from the E3 ligase complex, promotes the binding of VHL30 to a protein arginine methyltransferase, PRMT3 PMID: 21942715
  7. The Tyr87Cys and Tyr87Glu-PRMT3 variants had markedly decreased affinity to ribosomal protein S2 and, consequently, reduced enzymatic activity compared to the wild-type enzyme. PMID: 21059412
  8. PRMT3 is a ribosomal protein methyltransferase that affects the cellular level of ribosomal subunits. PMID: 15175657
  9. DAL-1/4.1B protein significantly inhibits PRMT3 methylation of cellular substrates, which may affect mechanism through which DAL-1/4.1B affects tumor cell growth. PMID: 15334060
  10. Type I Arginine Methyltransferases PRMT1 and PRMT-3 Act Distributively PMID: 19158082
  11. results suggest that the pathological mutation in the PABPN1 gene alters the protein conformation and induces a preferential interaction with type I PRMTs and Hsp70 chaperones PMID: 19641605

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Subcellular Location Cytoplasm
Protein Families Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
Database Links

HGNC: 30163

OMIM: 603190

KEGG: hsa:10196

STRING: 9606.ENSP00000331879

UniGene: Hs.152337

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